Publikationen Bioverfahrenstechnik


Publikationen in Zeitschriften



[BioVT-2013-04]
Anja Wilming, Jens Begemann, Stefan Kuhne, Lars Regestein, Johannes Bongaerts, Stefan Evers, Karl-Heinz Maurer, Jochen Büchs: Metabolic studies of -polyglutamic acid production in Bacillus licheniformis by small-scale continuous cultivations. Biochemical Engineering Journal, 2013, 73, 29-37


[BioVT-2013-03]
Tino Schlepütz, John Paul Gerhards, Jochen Büchs: Ensuring constant oxygen supply during inoculation is essential to obtain reproducible results with obligatory aerobic acetic acid bacteria in vinegar production. Process Biochemistry, 2013, 48(3), 398-405


[BioVT-2013-01]
Lars Regestein, Thomas Maskow, Andreas Tack, Ingo Knabben, Martin Wunderlich, Johannes Lerchner, Jochen Büchs: Non-invasive online detection of microbial lysine formation in stirred tank bioreactors by using calorespirometry. Biotechnology and Bioengineering, 2013, 110(5), 1386-1395


[BioVT-2012-08]
Lars Regestein, Heiner Giese, Michael Zavrel, Jochen Büchs: Comparison of two methods for designing calorimeters using stirred tank reactors. Biotechnology and Bioengineering, 2013, 110(1), 180-190


[BioVT-2012-19]
Martin Kunze, Robert Huber, Claudia Gutjahr, Stefan Müllner, Jochen Büchs: Predictive tool for recombinant protein production in E. coli shake flask cultures using an on-line monitoring system. Biotechnology Progress, 2012, 28(1), 103-113


[BioVT-2012-18]
Cornelia Bähr, Bernd Leuchtle, Christian Lehmann, Julia Becker, Markus Jeude, Frank Peinemann, René Arbter, Jochen Büchs: Dialysis shake flask for effective screening in fed-batch mode. Biochemical Engineering Journal, 2012, 69, 182-195


[BioVT-2012-17]
Kazuhito Nagayama, Antje Spieß, Jochen Büchs: Enhanced catalytic performance of immobilized Parvibaculum lavamentivorans alcohol dehydrogenase in a gas phase bioreactor using glycerol as an additive. Chemical Engineering Journal, 2012, 207–208(1), 342–348


[BioVT-2012-16]
Anna Voll, Tobias Klement, Gero Gerhards, Jochen Büchs, Wolfgang Marquardt: Metabolic Modelling of Itaconic Acid Fermentation with Ustilago maydis. Chemical Engineering Transactions, 2012, 27, 367-372


[BioVT-2012-15]
Sven Hansen, Ioanna Hariskos, Bettina Luchterhand, Jochen Büchs: Development of a modified Respiration Activity Monitoring System for accurate and highly resolved measurement of respiration activity in shake flask fermentations. Journal of Biological Engineering, 2012, 6:11


[BioVT-2012-14]
Jozef Kochan, Marco Scheidle, Joost van Erkel, Matías Bikel, Jochen Büchs, John Erik Wong, Thomas Melin, Matthias Wessling: Characterization of antibacterial polyethersulfone membranes using the respiration activity monitoring system (RAMOS). Water Research, 2012, 46(16), 5401–5409


[BioVT-2012-13]
Eva-Maria Siepert, Esther Gartz, Mehmet Kemal Tur, Heinrich Delbrück, Stefan Barth, Jochen Büchs: Short-chain fluorescent tryptophan tags for online detection of functional recombinant proteins. BMC Biotechnology, 2012, 12:65


[BioVT-2012-12]
N. Mehmood, E. Olmos, J.-L. Goergen, F. Blanchard, P. Marchal, Wolf Klöckner, Jochen Büchs, S. Delaunay: Decoupling of oxygen transfer and power dissipation for the study of the production of pristinamycins by Streptomyces pristinaespiralis in shaking flasks. Biochemical Engineering Journal, 2012, 68, 25-33


[BioVT-2012-11]
Cinthia Núnez, Carlos Pena, Wolf Klöckner, Alberto Hernández-Eligio, Alexander V. Bogachev, Soledad Moreno, Josefina Guzmán, Jochen Büchs, Guadalupe Espin: Alginate synthesis in Azotobacter vinelandii is increased by reducing the intracellular production of ubiquinone. Applied Microbiology and Biotechnology, 2012, 97(6), 2503-2512


[BioVT-2012-10]
Gernot Jäger, Jochen Büchs: Biocatalytic conversion of lignocellulose to platform chemicals. Biotechnology Journal, 2012, 7(9), 1122–1136


[BioVT-2012-09]
Lars Regestein, Antje Wolf, Hans-Jürgen Schneider, Thomas Maskow, Florian Mertens, Jochen Büchs, Johannes Lerchner: A chip calorimeter for the monitoring of conventional bioreactors at elevated cell concentrations. Thermochimica Acta, 2012, 544, 10-16


[BioVT-2012-06]
Janko Potzkei, Martin Kunze, Thomas Drepper, Thomas Gensch, Karl-Erich Jaeger, Jochen Büchs: Real-time determination of intracellular oxygen in bacteria using a genetically encoded FRET-based biosensor. BMC Biology, 2012, 10:28


[BioVT-2012-05]
Wolf Klöckner, Jochen Büchs: Advances in shaking technologies. Trends in Biotechnology, 2012, 30(6), 307-314


[BioVT-2012-04]
Wolf Klöckner, Stephanie Tissot, Florian Wurm, Jochen Büchs: Power input correlation to characterize the hydrodynamics of cylindrical orbitally shaken bioreactors. Biochemical Engineering Journal, 2012, 65, 63-69


[BioVT-2012-03]
Tobias Klement, Sofia Milker, Gernot Jäger, Philipp M Grande, Pablo Domínguez de María, Jochen Büchs: Biomass pretreatment affects Ustilago maydis in producing itaconic acid. Microbial Cell Factories, 2012, 11:43


[BioVT-2012-02]
Werner Eberhard, Gernot Jäger, João P. C. Pinto, Antje Spieß, Jochen Büchs: Determining complete suspension of immobilized enzymes by analysis of digital camera images. Chemical Engineering Communications, 2012, 199(6), 720-736


[BioVT-2012-01]
David Ullisch, Christina A. Müller, Sabrina Maibaum, Janina Kirchhoff, Andreas Schiermeyer, Stefan Schillberg, Jean L. Roberts, Wiltrud Treffenfeldt, Jochen Büchs: Comprehensive characterization of two different Nicotiana tabacum cell lines leads to doubled GFP and HA protein production by media optimization. Journal of Bioscience and Bioengineering, 2012, 113(2), 242-248


[BioVT-2011-20]
Cornelia Bähr, Elisabeth Stammen, Regina Thiele, Stefan Böhm, Klaus Dilger, Jochen Büchs: Withstanding frequent steam sterilisation: Innovative technique to bond glass and stainless steel composites in biotechnology and endoscopic medicine. International Journal of Adhesion and Adhesives, 2012, 33(1), 15-25


[BioVT-2011-13]
Martin Kunze, Robert Huber, Claudia Gutjahr, Stefan Müllner, Jochen Büchs: Predictive tool for recombinant protein production in E. coli shake flask cultures using an on-line monitoring system. Biotechnology Progress, 2012, 1(28), 103-113


[BioVT-2011-21]
Kazuhito Nagayama, Antje Spieß, Jochen Büchs: Continuous stereoselective reduction catalyzed by thermophilic alcohol dehydrogenase in a gas phase bioreactor. Journal of Chemical Engineering of Japan, 2011, 44(12), 995-998


[BioVT-2011-17]
Thomas Maskow, Torsten Schubert, Antje Wolf, Friederike Buchholz, Lars Regestein, Jochen Büchs, Florian Mertens, Hauke Harms, Johannes Lerchner: Potentials and limitations of miniaturized calorimeters for bioprocess monitoring. Applied Microbiology and Biotechnology, 2011, 92(1), 55-66


[BioVT-2011-15]
Cornelia Bähr, Elisabeth Stammen, Sarah Zahlten, Stefan Böhm, Klaus Dilger, Jochen Büchs: Refining bioreactor design using autoclavable glass bonding. Advances in Bioscience and Biotechnology, 2011, 2(4), 233-243


[BioVT-2011-14]
Gernot Jäger, Michele Girfoglio, Florian Dollo, Roberto Rinaldi, Hans Bongard, Ulrich Commandeur, Rainer Fischer, Antje Spieß, Jochen Büchs: How recombinant swollenin from Kluyveromyces lactis affects cellulosic substrates and accelerates their hydrolysis. Biotechnology for Biofuels, 2011, 4(1), 33


[BioVT-2011-12]
Alvaro R. Lara, Ingo Knabben, Lars Regestein, Jamalledine Sassi, Luis Caspeta, Octavio T. Ramirez, Jochen Büchs: Comparison of oxygen enriched air vs. pressurized cultivations to increase oxygen transfer and to scale-up plasmid DNA production fermentations. Engineering in Life Science, 2011, 11(4), 382-386


[BioVT-2011-11]
Tobias Klement, Lydia Dankmeyer, Ronald Hommes, Piet van Solingen, Jochen Büchs: Acetate-glycerol cometabolism: cultivating Schizosaccharomyces pombe on a non-fermentable carbon source in a defined minimal medium. Journal of Bioscience and Bioengineering, 2011, 112(1), 20-25


[BioVT-2011-10]
Hamed Osouli Tabrizi, Ghassem Amoabediny, Behzad Moshiri, Mahdi Pesaran Haji Abbas, Behdad Pouran, Emad Imenipour, Hamid Rashedi, Jochen Büchs: Novel dynamic model for aerated shaking bioreactors. Biotechnology and Applied Biochemistry, 2011, 58(2), 128-137


[BioVT-2011-09]
N. Mehmood, E. Olmos, J.-L. Goergen, F. Blanchard, David Ullisch, Wolf Klöckner, Jochen Büchs, S. Delaunay: Oxygen supply controls the onset of pristinamycins production by Streptomyces pristinaespiralis in shaking flasks. Biotechnology and Bioengineering, 2011, 108(9), 2151-2161


[BioVT-2011-08]
Robert Huber, Helene Wulfhorst, Lukas Maksym, Regina Stehr, Martin Pöhnlein, Gernot Jäger, Antje Spieß, Jochen Büchs: Screening for enzyme activity in turbid suspensions with scattered light. Biotechnology Progress, 2011, 27(2), 555-561


[BioVT-2011-07]
Sven Hansen, Frank Kensy, Andreas Käser, Jochen Büchs: Potential errors in conventional DOT measurement techniques in shake flasks and verification using a rotating flexitube optical sensor. BMC Biotechnology, 2011, 11:49


[BioVT-2011-06]
Robert Huber, Simon Roth, Natalie Rahmen, Jochen Büchs: Utilizing high-throughput experimentation to enhance specific productivity of an E.coli T7 expression system by phosphate limitation. BMC Biotechnology, 2011, 11(1), 22


[BioVT-2011-05]
Marco Scheidle, Barbara Dittrich, Johannes Klinger, Hideo Ikeda, Doris Klee, Jochen Büchs: Controlling pH in shake flasks using polymer-based controlled release discs with pre-determined release kinetics. BMC Biotechnology, 2011, 11:25


[BioVT-2011-04]
Ingo Knabben, Lars Regestein, Julia Schauf, Sven Steinbusch, Jochen Büchs: Linear correlation between on-line capacitance and off-line biomass measurement up to high cell densities in Escherichia coli fermentations in a pilot-scale pressurized bioreactor. Journal of Microbiology and Biotechnology, 2011, 21(2), 204-211


[BioVT-2011-03]
Carlos Pena, Enrique Galindo, Jochen Büchs: The viscosifying power, degree of acetylation and molecular mass of the alginate produced by Azotobacter vinelandii in shake flasks are determined by the oxygen tranfer rate. Process Biochemistry, 2011, 46, 290-297


[BioVT-2011-02]
Rung-Kai Tan, Werner Eberhard, Jochen Büchs: Measurement and characterization of mixing time in shake flasks. Chemical Engineering Science, 2011, 66(3), 440-447


[BioVT-2011-01]
Gernot Jäger, Helene Wulfhorst, Erik Zeithammel, Eftimia Elinidou, Antje Spieß, Jochen Büchs: Screening of cellulases for biofuel production: Online monitoring of the enzymatic hydrolysis of insoluble cellulose using high-throughput scattered light detection. Biotechnology Journal, 2011, 6(1), 74-85


[BioVT-2010-20]
Ghassem Amoabediny, Jochen Büchs: Determination of CO2 sensitivity of micro-organisms in shaken bioreactors. I. Novel method based on the resistance of sterile closure. Biotechnology and Applied Biochemistry, 2010, 57(4), 157-166


[BioVT-2010-19]
Ghassem Amoabediny, Mahdi Pesaran Haji Abbas, Jochen Büchs: Determination of CO2 sensitivity of micro-organisms in shaken bioreactors. II. Novel online monitoring method. Biotechnology and Applied Biochemistry, 2010, 57(4), 167-175


[BioVT-2010-18]
Matthias Funke, Andreas Buchenauer, Wilfried Mokwa, Stefanie Kluge, Lea Hein, Carsten Müller, Frank Kensy, Jochen Büchs: Bioprocess control in Microscale: Scalable fermentations in disposable and user-friendly microfluidic systems. Microbial Cell Factories, 2010, 9:86


[BioVT-2010-17]
Thomas Drepper, Robert Huber, Achim Heck, Franco Circolone, Ann-Kathrin Hillmer, Jochen Büchs, Karl-Erich Jaeger: Flavin Mononucleotide-based fluorescent reporter proteins outperform GFP-like proteins as quantitative in vivo real-time reporters. Applied and Environmental Microbiology, 2010, 76(17), 5990-5994


[BioVT-2010-16]
Thomas Palmen, Jens Nieveler, Bettina Frölich, Wiltrud Treffenfeldt, Martina Pohl, Jochen Büchs: Physiological relation between respiration activity and heterologous expression of selected benzoylformate decarboxylase variants in Escherichia coli. Microbial Cell Factories, 2010, 9:76


[BioVT-2010-15]
Philip Engel, Radoslav Mladenov, Helene Wulfhorst, Gernot Jäger, Antje Spieß: Point by Point Analysis: How Ionic liquids effect the enzymatic hydrolysis of native and modified cellulose. Green Chemistry, 2010, 12, 1959–1966


[BioVT-2010-14]
Roberto Rinaldi, Philip Engel, Jochen Büchs, Antje Spieß, Ferdi Schüth: An integrated catalytic approach to fermentable sugars from cellulose. ChemSusChem, 2010, 3(10), 1151-1153


[BioVT-2010-13]
Matthias Funke, Andreas Buchenauer, Uwe Schnakenberg, Wilfried Mokwa, Sylvia Diederichs, Alan Mertens, Carsten Müller, Frank Kensy, Jochen Büchs: Microfluidic biolector-microfluidic bioprocess control in microtiter plates. Biotechnology and Bioengineering, 2010, 107(3), 497-505


[BioVT-2010-12]
Kazuhito Nagayama, Antje Spieß, Jochen Büchs: Gas phase enantioselective reduction catalyzed by immobilized ketoreductase: Effects of water activity and reaction temperature. Biochemical Engineering Journal, 2010, 52, 301-303


[BioVT-2010-11]
Ingo Knabben, Lars Regestein, Frank Marquering, Sven Steinbusch, Alvaro R. Lara, Jochen Büchs: High cell-density processes in batch mode of a genetically engineered Escherichia coli strain with minimized overflow metabolism using a pressurized bioreactor. Journal of Biotechnology, 2010, 150, 73-79


[BioVT-2010-10]
Robert Huber, Thomas Palmen, Nadine Ryk, Ann-Kathrin Hillmer, Karina Luft, Frank Kensy, Jochen Büchs: Replication methods and tools in high-throughput cultivation processes - recognizing potential variations of growth and product formation by on-line monitoring. Bmc Biotechnology, 2010, 10:22


[BioVT-2010-09]
Ingo Knabben, Lars Regestein, Carsten Grumbach, Sven Steinbusch, Gotthard Kunze, Jochen Büchs: Online determination of viable biomass up to very high cell densities in Arxula adeninivorans fermentations using an impedance signal. Journal of Biotechnology, 2010, 149, 60-66


[BioVT-2010-08]
Kirsten Kottmeier, Carsten Müller, Robert Huber, Jochen Büchs: Increased product formation induced by a directed secondary substrate limitation in a batch Hansenula polymorpha culture. Applied Microbiology and Biotechnology, 2010, 86(1), 93-101


[BioVT-2010-06]
Gernot Jäger, Zhuojun Wu, Kerstin Garschhammer, Philip Engel, Tobias Klement, Roberto Rinaldi, Antje Spieß, Jochen Büchs: Practical screening of purified cellobiohydrolases and endoglucanases with alpha-cellulose and specification of hydrodynamics. Biotechnology for biofuels, 2010, 3:18


[BioVT-2010-05]
Kazuhito Nagayama, Antje Spieß, Jochen Büchs: Immobilization conditions of ketoreductase on enantioselective reduction in a gas-solid bioreactor. Biotechnology Journal, 2010, 5(5), 520-525


[BioVT-2010-04]
Mirko C. Hofmann, Matthias Funke, Jochen Büchs, Wilfried Mokwa, Uwe Schnakenberg: Development of a four electrode sensor array for impedance spectroscopy in high content screenings of fermentation processes. Sensors and Actuators B: Chemical, 2010, 147(1), 93-99


[BioVT-2010-03]
Michael Zavrel, Claas Michalik, Tilman Schwendt, Thomas Schmidt, Marion Ansorge-Schumacher, Christoph Janzen, Wolfgang Marquardt, Jochen Büchs, Antje Spieß: Systematic determination of intrinsic reaction parameters in enzyme immobilizates. Chemical Engineering Science, 2010, 65(8), 2491-2499


[BioVT-2010-02]
Helene Wulfhorst, Gernot Jäger, Efthimia Ellinidou, Jochen Büchs, Antje Spieß: Charakterisierung von Cellulasepräparationen mittels Streulicht. Chemie Ingenieur Technik, 2010, 82(1-2), 117-120


[BioVT-2010-01]
Marco Scheidle, Markus Jeude, Barbara Dittrich, Sylvia Denter, Frank Kensy, Manfred Suckow, Doris Klee, Jochen Büchs: High-throughput screening of Hansenula polymorpha clones in the batch compared with the controlled-release fed-batch mode on a small scale. FEMS Yeast Research, 2010, 10(1), 83-92


[BioVT-2009-32]
Ghassem Amoabediny, Yaser Ziaie-Shirkolaee, Jochen Büchs: Development of an unsteady-state model for a biological system in miniaturized bioreactors. Biotechnology and Applied Biochemistry, 2009, 54(3), 163-170


[BioVT-2009-31]
Kerasina Dimoula, Martina Pohl, Jochen Büchs, Antje Spieß: Substrate and water adsorption phenomena in a gas/solid enzymatic reactor. Biotechnology Journal, 2009, 4(5), 712-721


[BioVT-2009-28]
Frank Kensy, Christoph Engelbrecht, Jochen Büchs: Scale-up from microtiter plate to laboratory fermenter: evaluation by online monitoring techniques of growth and protein expression in Escherichia coli and Hansenula polymorpha fermentations. Microbial Cell Factories, 2009, 8:68


[BioVT-2009-26]
Robert Huber, Marco Scheidle, Barbara Dittrich, Doris Klee, Jochen Büchs: Equalizing growth in high-throughput small scale cultivations via precultures operated in fed-batch mode. Biotechnology and Bioengineering, 2009, 103(6), 1095-1102


[BioVT-2009-22]
Matthias Funke, Sylvia Diederichs, Frank Kensy, Carsten Müller, Jochen Büchs: The baffled microtiter plate - increased oxygen transfer and improved online-monitoring in small scale fermentations.. Biotechnology and Bioengineering, 2009, 103(6), 1118-1128


[BioVT-2009-20]
Christoph Stöckmann, Marco Scheidle, Barbara Dittrich, Armin Merckelbach, Grit Hehmann, Georg Melmer, Doris Klee, Jochen Büchs, Hyun Ah Kang, Gerd Gellissen: Process developement in Hansenula polymorpha and Arxula adeninivorans, a re-assessment. Microbial Cell Factories, 2009, 8:22


[BioVT-2009-19]
Andreas Buchenauer, Mirko C. Hofmann, Matthias Funke, Jochen Büchs, Wilfired Mokwa, Uwe Schnakenberg: Micro-bioreactors for fed-batch fermentations with integrated online monitoring and microfluidic devices. Biosensors, 2009, 24(5), 1411-1416


[BioVT-2009-18]
Kirill Rachinskiy, Hergen Schultze, Matthias Boy, Uwe Bornscheuer, Jochen Büchs: Enzyme test bench: a high throughput enzyme characterization technique including the long term stability. Biotechnology and Bioengineering, 2009, 103(2), 305-322


[BioVT-2009-17]
Kirsten Kottmeier, Jost Weber, Carsten Müller, Thomas Bley, Jochen Büchs: Asymmetric division of Hansenula polymorpha reflected by a drop of light scatter intensity measured in batch microtiter plate cultivations at phosphate limitation. Biotechnology and Bioengineering, 2009, 104(3), 554-561


[BioVT-2009-16]
Andreas Buchenauer, Matthias Funke, Jochen Büchs, Wilfried Mokwa, Uwe Schnakenberg: Microbioreactors with microfluidic control and a user-friendly connection to the actuator hardware. Journal of Micromechanics and Microengineering, 2009, 19:7


[BioVT-2009-15]
Robert Huber, Daniel Ritter, Till Hering, Ann-Kathrin Hillmer, Frank Kensy, Carsten Müller, Le Wang, Jochen Büchs: Robo-Lector - a novel platform for automated high-throughput cultivations in microtiter plates with high information content. Microbial Cell Factories, 2009, 8:42


[BioVT-2009-06]
Frank Kensy, Emerson Zang, Christian Faulhammer, Rung-Kai Tan, Jochen Büchs: Validation of a high-throughput fermentation system based on online monitoring of biomass and fluorescence in continuously shaken microtiter plates. Microbial Cell Factories, 2009, 8:31


[BioVT-2009-05]
Renaud J. Mikolajek, Antje Spieß, Martina Pohl, Jochen Büchs: Propioin synthesis using Thiamine Diphosphate-dependent enzymes. Biotechnology Progress, 2009, 25(1), 132-138


[BioVT-2009-04]
Michael Zavrel, Daniela Bross, Matthias Funke, Jochen Büchs, Antje Spieß: High-throughput screening for ionic liquids dissolving (ligno-)cellulose. Bioresource Technology, 2009, 100(9), 2580-2587


[BioVT-2008-20]
Keyur Raval, Yoshihito Kato, Jochen Büchs: Extended method to evaluate power consumption in large disposable shaking bioreactors. Journal of Chemical Engineering of Japan, 2008, 41(11), 1075-1082


[BioVT-2008-19]
Kirill Rachinskiy, Hergen Schultze, Matthias Boy, Jochen Büchs: Enzyme test bench: a biochemical application of the multirate modeling. Journal of Physics Conference Series, 2008, 138(2), 1-14


[BioVT-2008-12]
M. Peters, Michael Zavrel, J. Kahlen, T. Schmidt, M. Ansorge-Schumacher, W. Leitner, Jochen Büchs, L. Greiner, Antje Spieß: Systematic Approach to Solvent Selection for Biphasic Systems with a Combination of COSMO-RS and a Dynamic Modeling Tool. Engineering in Life Sciences, 2008, 8(5), 546-552


[BioVT-2008-06]
Antje Spieß, Michael Zavrel, Marion Ansorge-Schumacher, Christoph Janzen, Claas Michalik, Thomas Schmidt, Tilman Schwendt, Jochen Büchs, Reinhart Poprawe, Wolfgang Marquardt: Model discrimination for the propionic acid diffusion into hydrogel beads using lifetime confocal laser scanning microscopy. Chemical Engineering Science, 2008, 63(2), 3457-3465


[BioVT-2008-05]
Antje Spieß, Werner Eberhard, Martina Peters, Marrit F. Eckstein, Lasse Greiner, Jochen Büchs: Prediction of partition coefficients using COSMO-RS: Solvent screening for maximum conversion in biocatalytic two-phase reaction systems. Chemical Engineering and Processing, 2008, 47(2), 1034-1041


[BioVT-2008-04]
Michael Zavrel, Thomas Schmidt, Claas Michalik, Marion Ansorge-Schumacher, Wolfgang Marquardt, Jochen Büchs, Antje Spieß: Mechanistic kinetic model for symmetric carboligations using benzaldehyde lyase. Biotechnology and Bioengineering, 2008, 101(1), 27-38


[BioVT-2008-03]
J.S. Guez, C.H. Muller, P. M. Danze, Jochen Büchs, P. Jacques: Respiration activity monitoring system (RAMOS), an efficient tool to study the influence of the oxygen transfer rate on the synthesis of lipopeptide by Bacillus subtilis ATCC6633. Journal of Biotechnology, 2008, 134(1-2), 121-126


[BioVT-2008-02]
Ali Akgün, Carsten Müller, Ramona Engmann, Jochen Büchs: Application of an improved continuous parallel shaken bioreactor system for three microbial model systems. Bioprocess and Biosystems Engineering, 2008, 31(3), 193-205


[BioVT-2007-17]
Claas Michalik, Thomas Schmidt, Michael Zavrel, Marion Ansorge-Schumacher, Antje Spieß, Wolfgang Marquardt: Application of the incremental identification method to the formate oxidation using formate dehydrogenase. Chemical Engineering Science, 2007, 62, 5592-5597


[BioVT-2007-13]
Martina Peters, Marrit F. Eckstein, Gert Hartjen, Antje Spieß, Walter Leitner, Lasse Greiner: Exploring conversion of biphasic catalytic reactions: Analytical solution and parameter study. Industrial Engineering and Chemistry Research, 2007, 46(11), 7073-7078


[BioVT-2007-11]
Marco Scheidle, Johannes Klinger, Jochen Büchs: Combination of on-line pH and oxygen transfer measurement in shake flasks by Fiber Optical Technique and Respiration Activity Monitoring System (RAMOS). Sensors, 2007, 7(1), 3472-3480


[BioVT-2007-10]
Tibor Anderlei, Christian Mrotzek, Stefan Bartsch, Ghassem Amoabediny, Cyril P. Peter, Jochen Büchs: New method to determine the mass transfer resistance of sterile closures for shaken bioreactors. Biotechnology and Bioengineering, 2007, 98(5), 999-1007


[BioVT-2007-09]
Arndt Knoll, Kirsten Schroer, Bernward Husemann, Betina Ribeiro, Stefan Bartsch, Philip Engel, Christoph Stöckmann, Juri Seletzky, Jochen Büchs: High cell density cultivation of recombinant yeasts and bacteria under non-pressurized and pressurized conditions in stirred tank bioreactors. Journal of Biotechnology, 2007, 132(2), 167-179


[BioVT-2007-08]
Carlos Pena, Cyril P. Peter, Jochen Büchs, Enrique Galindo: Evolution of the specific power input and oxygen transfer rate in alginate-producing cultures of Azotobacter vinelandii conducted in shake flasks. Biochemical Engineering Journal, 2007, 36(2), 73-80


[BioVT-2007-07]
Juri M. Seletzky, Ute Noack, Jens Fricke, Eike Welk, Werner Eberhard, Christof Knocke, Jochen Büchs: Scale-up from shake flasks to fermenters in batch and continuous mode with Corynebacterium glutamicum on lactic acid based on oxygen transfer and pH. Biotechnology and Bioengineering, 2007, 98(4), 800-811


[BioVT-2007-06]
Renaud Mikolajek, Antje Spieß, Jochen Büchs: Feasibility of gas/solid carboligation: conversion of benzaldehyde to benzoin using thiamine diphosphate dependent enzymes. Journal of Biotechnology, 2007, 129(4), 723-725


[BioVT-2007-05]
Ghassem Amoabediny, Jochen Büchs: Modelling and advanced understanding of unsteady-state gas transfer in shaking bioreactors. Biotechnology and Applied Biochemistry, 2007, 46(1), 57-67


[BioVT-2007-04]
Juri M. Seletzky, Ute Noack, Sebastian Hahn, Arndt Knoll, Ghassem Amoabediny, Jochen Büchs: An experimental comparison of respiration measuring techniques in fermenters and shake flasks: exhaust gas analyzer vs. RAMOS device vs. respirometer. Journal of Industrial Microbiology and Biotechnology, 2007, 34(2), 123-130


[BioVT-2007-03]
Carsten Bäumchen, Arndt Knoll, Bernward Husemann, Juri Seletzky, Bernd Maier, Carsten Dietrich, Ghassem Amoabediny, Jochen Büchs: Effect of elevated dissolved carbon dioxide concentrations on growth of Corynebacterium glutamicum on D-glucose and L-lactate. Journal of Biotechnology, 2007, 128(4), 868-874


[BioVT-2007-02]
Keyur Raval, Yoshihito Kato, Jochen Büchs: Comparison of torque method and temperature nethod for determination of power consumption in disposable shaken bioreactors. Biochemical Engineering Journal, 2007, 34(3), 224-227


[BioVT-2007-015]
Renauld J. Mikolajek, Antje Spieß, Martina Pohl, S. Lamare, Jochen Büchs: An activity, stability and selectivity comparison of propioin synthesis by thiamine diphosphate-dependent enzymes in a solid/gas bioreactor. ChemBioChem, 2007, 8(9), 1063-70


[BioVT-2007-01]
Jochen Büchs, Ulrike Maier, Stefan Lotter, Cyril P. Peter: Calculating liquid distribution in shake flasks on rotary shakers at waterlike viscosities. Biochemical Engineering Journal, 2007, 34(3), 200-208


[BioVT-2006-12]
Marrit F. Eckstein, Martina Peters, Julia Lembrecht, Antje Spieß, Lasse Greiner: Maximise your equilibrium conversion in biphasic catalysed reactions: Mathematical description and practical guideline.. Advanced Synthesis and Catalysis, 2006, 348, 1591-1596


[BioVT-2006-11]
Marrit F. Eckstein, Julia Lembrecht, J. Schumacher, Martina Peters, C. Roosen, Lasse Greiner, W. Eberhard, Antje Spieß, W. Leitner, U. Kragl: Maximise your equilibrium conversion in biphasic catalysed reactions: How to obtain equilibrum constants for reactions of practical relevance?. Advanced Synthesis and Catalysis, 2006, 348, 1597-1604


[BioVT-2006-10]
Keyur Raval, Chao-Min Liu, Jochen Büchs: Large-scale disposable shaking bioreactors: A promising choice. Bioprocess International, 2006, 4(1), 46, 48, 50


[BioVT-2006-09]
Cyril P. Peter, Yusuke Suzuki, Jochen Büchs: Hydromechanical stress in shake flasks: correlation for the maximum local energy dissipation rate. Biotechnology and Bioengineering, 2006, 93(6), 1164-1176


[BioVT-2006-08]
Archana H. Trivedi, Antje Spieß, Thomas Daussmann, Jochen Büchs: Study on mesophilic and thermophilic alcohol dehydrogenases in gas-phase reaction. Biotechnology Progress, 2006, 22(2), 454-458


[BioVT-2006-07]
Cyril P. Peter, Yusuke Suzuki, Kirill Rachinskiy, Stefan Lotter, Jochen Büchs: Volumetric power consumption in baffled shake flasks. Chemical Engineering Science, 2006, 61(11), 3771-3779


[BioVT-2006-06]
Archana H. Trivedi, Antje Spieß, Thomas Daussmann, Jochen Büchs: Effect of additives on gas-phase catalysis with immobilised Thermoanaerobacter species alcohol dehydrogenase (ADH T). Applied Microbiology and Biotechnology, 2006, 71(4), 407-414


[BioVT-2006-05]
Marion B. Ansorge-Schumacher, Sonja Steinsiek, Werner Eberhard, Nikolaos Keramidas, Klaus Erkens, Winfried Hartmeier, Jochen Büchs: Assaying CO2 release for determination of formate dehydrogenase activity in entrapment matrices and aqueous-organic two-phase systems. Biotechnology and Bioengineering, 2006, 95(1), 199-203


[BioVT-2006-04]
Markus Jeude, Barbara Dittrich, H. Niederschulte, Tibor Anderlei, Christof Knocke, Doris Klee, Jochen Büchs: Fed-batch mode in shake flasks by slow-release technique. Biotechnology and Bioengineering, 2006, 95(3), 433-445


[BioVT-2006-03]
Juri M. Seletzky, Ute Noack, Jens Fricke, Sebastian Hahn, Jochen Büchs: Metabolic activity of Corynebacterium glutamicum grown on L: -lactic acid under stress. Applied Microbiology and Biotechnology, 2006, 72(6), 1297-1307


[BioVT-2006-02]
Hartmut F. Zimmermann, Tibor Anderlei, Jochen Büchs, Michael Binder: Oxygen limitation is a pitfall during screening for industrial strains. Applied Microbiology and Biotechnology, 2006, 72(6), 1157-1160


[BioVT-2006-01]
Juri M. Seletzky, K. Otten, Stefan Lotter, Jens Fricke, Cyril P. Peter, H. R. Maier, Jochen Büchs: A simple and inexpensive method for investigating microbiological, enzymatic, or inorganic catalysis using standard histology and microbiology laboratory equipment: assembly, mass transfer properties, hydrodynamic conditions and evaluation. Biotechnic & Histochemistry, 2006, 81(4-6), 133-138


[BioVT-2005-10]
Frank Kensy, Hartmut F. Zimmermann, Ingo Knabben, Tibor Anderlei, Harald Trauthwein, Uwe Dingerdissen, Jochen Büchs: Oxygen transfer phenomena in 48-well microtiter plates: determination by optical monitoring of sulfite oxidation and verification by real-time measurement during microbial growth. Biotechnology and Bioengineering, 2005, 89(6), 698-708


[BioVT-2005-09]
Matthias Heinemann, Holger Meinberg, Jochen Büchs, Hans-Jürgen Koss, Marion B. Ansorge-Schumacher: Method for quantitative determination of spatial polymer distribution in alginate beads using Raman spectroscopy. Applied Spectroscopy, 2005, 59(3), 280-285


[BioVT-2005-08]
Arnd Knoll, Bernd Maier, Hermann Tscherrig, Jochen Büchs: The oxygen mass transfer, carbon dioxide inhibition, heat removal, and the energy and cost efficiencies of high pressure fermentation. Advances in Biochemical Engineering/Biotechnology, 2005, 92, 77-99


[BioVT-2005-07]
Archana H. Trivedi, Matthias Heinemann, Antje Spieß, Thomas Daussmann, Jochen Büchs: Optimization of adsorptive immobilization of alcohol dehydrogenases. Journal of Bioscience and Bioengineering, 2005, 99(4), 340-347


[BioVT-2005-05]
M. Samorski, G. Müller-Newen, Jochen Büchs: Quasi-continuous combined scattered light and fluorescence measurements: A novel measurement technique for shaken microtiter plates. Biotechnology and Bioengineering, 2005, 92(1), 61-68


[BioVT-2005-04]
Mirko C. Hofmann, Frank Kensy, Jochen Büchs, Wilfried Mokwa, Uwe Schnakenberg: Transponder-based sensor for monitoring electrical properties of biological cell solutions. Journal of Bioscience and Bioengineering, 2005, 100(2), 172-177


[BioVT-2005-03]
Mirko C. Hofmann, D. Ellersiek, Frank Kensy, Jochen Büchs, Wilfried Mokwa, Uwe Schnakenberg: Galvanic decoupled sensor for monitoring biomass concentration during fermentation processes. Sensors and Actuators B: Chemical, 2005, 111, 370-375


[BioVT-2005-02]
Frank Kensy, G. T. John, B. Hofmann, Jochen Büchs: Characterisation of operation conditions and online monitoring of physiological culture parameters in shaken 24-well microtiter plates. Bioprocess and Biosystems Engineering, 2005, 28(2), 75-81


[BioVT-2005-01]
Andreas Buthe, Tobias Recker, Matthias Heinemann, Winfried Hartmeier, Jochen Büchs, Marion B. Ansorge-Schumacher: pH-optima in lipase-catalysed esterification. Biocatalysis and Biotransformation, 2005, 23(5), 307-314


[BioVT-2004-11]
Matthias Heinemann, Ute Limper, Jochen Büchs: New insights in the spatially resolved dynamic pH measurement in macroscopic large absorbent particles by confocal laser scanning microscopy. Journal of Chromatography A, 2004, 1024(1-2), 45-53


[BioVT-2004-10]
Cyril P. Peter, Stefan Lotter, Ulrike Maier, Jochen Büchs: Impact of out-of-phase conditions on screening results in shaking flask experiments. Biochemical Engineering Journal, 2004, 17(3), 205-215


[BioVT-2004-09]
Stefan Lotter, Jochen Büchs: Utilization of specific power input measurements for optimization of culture conditions in shaking flasks. Biochemical Engineering Journal, 2004, 17(3), 195-203


[BioVT-2004-08]
Tibor Anderlei, Werner Zang, Manfred Papaspyrou, Jochen Büchs: Online respiration activity measurement (OTR, CTR, RQ) in shake flasks. Biochemical Engineering Journal, 2004, 17(3), 187-194


[BioVT-2004-07]
Philipp B. Danielson, Jochen Büchs, Christoph Stockmann, James C. Fogleman: Maximizing cell densities in miniprep-scale cultures with H15 medium and improved oxygen transfer. Biochemical Engineering Journal, 2004, 17(3), 175-180


[BioVT-2004-06]
Ulrike Maier, Mario Losen, Jochen Büchs: Advances in understanding and modeling the gas-liquid mass transfer in shake flasks. Biochemical Engineering Journal, 2004, 17(3), 155-167


[BioVT-2004-04]
Carla Ferloni, Matthias Heinemann, Werner Hummel, Thomas Daussmann, Jochen Büchs: Optimization of enzymatic gas-phase reactions by increasing the long-term stability of the catalyst. Biotechnology Progress, 2004, 20(3), 975-978


[BioVT-2004-03]
Yoshihito Kato, Cyril P. Peter, Ali Akgün, Jochen Büchs: Power consumption and heat transfer resistance in large rotary shaking vessels. Biochemical Engineering Journal, 2004, 21(1), 83-91


[BioVT-2004-02]
Mario Losen, Bettina Frölich, Martina Pohl, Jochen Büchs: Effect of oxygen limitation and medium composition on Escherichia coli fermentation in shake-flask cultures. Biotechnology Progress, 2004, 20(4), 1062-1068


[BioVT-2004-01]
Ali Akgün, Bernd Maier, Diana Preis, Birthe Roth, Renata Klingelhofer, Jochen Büchs: A novel parallel shaken bioreactor system for continuous operation. Biotechnology Progress, 2004, 20(6), 1718-1724


[BioVT-2003-09]
Robert Hermann, Mathias Lehmann, Jochen Büchs: Characterization of gas-liquid mass transfer phenomena in microtiter plates. Biotechnology and Bioengineering, 2003, 81(2), 178-186


[BioVT-2003-07]
Yoshihito Kato, Setsuro Hiraoka, Yutaka Tada, Kimihito Hirose, Jochen Büchs: Mixing performance of a reciprocally shaking vessel. Journal of Chemical Engineering of Japan, 2003, 36(6), 663-667


[BioVT-2003-06]
M. Silberbach, B. Maier, M. Zimmermann, Jochen Büchs: Glucose oxidation by Gluconobacter oxydans: characterization in shaking-flasks, scale-up and optimization of the pH profile. Applied Microbiology and Biotechnology, 2003, 62(1), 92-98


[BioVT-2003-05]
Matthias Heinemann, Anne Kümmel, Ralf Giesen, Marion B. Ansorge-Schumacher, Jochen Büchs: Experimental and theoretical analysis of phase equilibria in a two-phase system used for biocatalytic esterifications. Biocatalysis and Biotransformation, 2003, 21(3), 115-121


[BioVT-2003-04]
Keyur Raval, Stephan Hellwig, Gunjan Prakash, Alfredo Ramos-Plasencia, Ashok Srivastava, Jochen Büchs: Necessity of a two-stage process for the production of azadirachtin-related limonoids in suspension cultures of Azadirachta indica. Journal of Bioscience and Bioengineering, 2003, 96(1), 16-22


[BioVT-2003-03]
Christoph Stöckmann, Mario Losen, Ulrike Dahlems, Christof Knocke, Gerd Gellissen, Jochen Büchs: Effect of oxygen supply on passaging, stabilising and screening of recombinant Hansenula polymorpha production strains in test tube cultures. FEMS Yeast Research, 2003, 4(2), 195-205


[BioVT-2003-02]
Yoshihito Kato, Setsuro Hiraoka, YutakaTada, Syoko Watanabe, Jochen Büchs: Solid-liquid mass transfer and critical frequency for complete suspension in a reciprocally shaking vessel. Journal of Chemical Engineering of Japan, 2003, 36(11), 1410-1414


[BioVT-2003-01]
Christoph Stöckmann, Ulrike Maier, Tibor Anderlei, Christof Knocke, Gerd Gellissen, Jochen Büchs: The oxygen transfer rate as key parameter for the characterization of Hansenula polymorpha screening cultures. Journal of Industrial Microbiology & Biotechnology, 2003, 30(10), 613-622


[BioVT-2002-02]
Matthias Heinemann, Thomas Wagner, Bastien Doumeche, Marion B. Ansorge-Schumacher, Jochen Büchs: A new approach for the spatially resolved qualitative analysis of the protein distribution in hydrogel beads based on confocal laser scanning microscopy. Biotechnology Letters, 2002, 24(10), 845-850


[BioVT-2002-01]
Bastien Doumeche, Matthias Heinemann, Jochen Büchs, Winfried Hartmeier, Marion B. Ansorge-Schumacher: Enzymatic catalysis in gel-stabilized two-phase systems: improvement of the solvent phase. Journal of Molecular Catalysis B-Enzymatic, 2002, 18(1-3), 19-27


[BioVT-2001-09]
Tibor Anderlei, Jochen Büchs: Device for sterile online measurement of the oxygen transfer rate in shaking flasks. Biochemical Engineering Journal, 2001, 7(2), 157-162


[BioVT-2001-08]
Jochen Büchs, Stefan Lotter, Claudia Milbradt: Out-of-phase operating conditions, a hitherto unknown phenomenon in shaking bioreactors. Biochemical Engineering Journal, 2001, 7(2), 135-141


[BioVT-2001-07]
Christian Mrotzek, Tibor Anderlei, Hans-Jürgen Henzler, Jochen Büchs: Mass transfer resistance of sterile plugs in shaking bioreactors. Biochemical Engineering Journal, 2001, 7(2), 107-112


[BioVT-2001-06]
Ulrike Maier, Jochen Büchs: Characterisation of the gas-liquid mass transfer in shaking bioreactors. Biochemical Engineering Journal, 2001, 7(2), 99-106


[BioVT-2001-05]
Jochen Büchs: Introduction to advantages and problems of shaken cultures. Biochemical Engineering Journal, 2001, 7(2), 91-98


[BioVT-2001-04]
Jochen Büchs, Bernd Zoels: Evaluation of maximum to specific power consumption ratio in shaking bioreactors. Journal of Chemical Engineering of Japan, 2001, 34(5), 647-653


[BioVT-2001-03]
Bernd Maier, Carsten Dietrich, Jochen Büchs: Correct application of the sulphite oxidation methodology of measuring the volumetric mass transfer coefficient k(L)a under non-pressurized and pressurized conditions. Food Bioprod. Process., 2001, 79(C2), 107-113


[BioVT-2001-02]
Robert Hermann, Nico Walther, Ulrike Maier, Jochen Büchs: Optical method for the determination of the oxygen-transfer capacity of small bioreactors based on sulfite oxidation. Biotechnology and Bioengineering, 2001, 74(5), 355-363


[BioVT-2000-03]
Jochen Büchs, Ulrike Maier, Claudia Milbradt, Bernd Zoels: Power consumption in shaking flasks on rotary shaking machines: II. Nondimensional description of specific power consumption and flow regimes in unbaffled flasks at elevated liquid viscosity. Biotechnology and Bioengineering, 2000, 68(6), 594-601


[BioVT-2000-02]
Jochen Büchs, Ulrike Maier, Claudia Milbradt, Bernd Zoels: Power consumption in shaking flasks on rotary shaking machines: I. Power consumption measurement in unbaffled flasks at low liquid viscosity. Biotechnology and Bioengineering, 2000, 68(6), 589-593


[BioVT-2000-01]
Wouter A. Duetz, Lorenz Rüedi, Robert Hermann, Kevin O'Connor, Jochen Büchs, Bernard Witholt: Methods for intense aeration, growth, storage, and replication of bacterial strains in microtiter plates. Applied and Environmental Microbiology, 2000, 66(6), 2641-2646


[BioVT-1999-01]
S. Schmidt, Jochen Büchs, C. Born, P. Biselli: A new correlation for the wall-to-fluid mass transfer in liquid-solid fluidized beds. Chemical Engineering Science, 1999, 54(6), 829-839


[BioVT-1988-02]
Jochen Büchs, Nava Mozes, Christian Wandrey, Paul G. Rouxhet: Cell adsorption control by culture conditions: Influence of phosphate on surface properties, flocculation and adsorption behaviour of corynebacterium glutamicum.. Applied Microbiology and Biotechnology, 1988, 29(2-3), 119-128


[BioVT-1985-01]
Jochen Büchs, Yoshimi Benno, Tomotari Mitsuoka, Shintaro Furusaki, Teruyuki Nagamune, Isao Endo: A New Automatic System to Evaluate the Density of Viable Microorganisms in Liquids. Systematic and Applied Microbiology, 1985, 6(2), 227-235



Publikationen in Büchern



[BioVT-2011-16]
Wolf Klöckner, Jochen Büchs: Shake-Flask Bioreactors. In: Murray Moo-Young (Eds.): Comprehensive Biotechnology, Elsevier, (2.17), 2011, 213-226


[BioVT-2007-19]
Arndt Knoll, Jochen Büchs: L-Lysine-Coupling of bioreaction and process model. In: E.Heinzle, A. Biwer, C. Cooney (Eds.): Development of sustainable Bioprocesses, (7), 2007, 156-167



Referierte Konferenzbeiträge



[BioVT-2009-38]
Cornelia Bähr, Regina Thiele, Stefan Böhm, Jochen Büchs: Autoklavierbare Glasklebtechnik für die Biotechnologie und Medizintechnik. In: 27. Jahrestagung der Biotechnologen, Mannheim, 08-10.09.2009


[BioVT-2009-37]
Cornelia Bähr, Regina Thiele, Stefan Böhm, Jochen Büchs: An autoclavable glass adhesion technique for biotechnology and medical devices. In: 14th European Congress on Biotechnology, Barcelona, Spain, 13-16.09.2009



Nicht referierte Beiträge



[BioVT-2009-30]
Marco Scheidle, Barbara Dittrich, Johannes Klinger, Lena Meißner, Doris Klee, Jochen Büchs: pH-Kontrolle in Schüttelkolben mit Hilfe neuartiger Controlled-Release-Systeme. Chemie Ingenieur Technik, 1246


[BioVT-2009-25]
Antje Spieß, Helene Wulfhorst: Biokatalyse in unkonventionellen Medien. RWTH Themen 2/2009 Verfahrenstechnik - Kreative Lösungen für morgen, 2009, 2, 42-43


[BioVT-2009-24]
Jochen Büchs, Matthias Funke, Tobias Klement: Vom Mikroliter zum Kubikmeter. RWTH Themen 2/2009 Verfahrenstechnik - Kreative Lösungen für morgen, 2009, 2, 10-13


[BioVT-2009-23]
Philip Engel, Helene Wulfhorst, Gernot Jäger, Radoslav Mladenov, Janys Pleßmann, Xin Lin, Antje Spieß, Jochen Büchs: Cellulose dissolution in ionic liquids and characterization of the enzymatic hydrolysis in the presence of ionic liquids. Chemie Ingenieur Technik, 1038


[BioVT-2009-21]
Elisabeth Stammen, Stefan Böhm, Klaus Dilger, Cornelia Bähr, Jochen Büchs: Glasklebungen - Den Belastungen der Dampfsterilisation gewachsen. Adhäsion Kleben & Dichten, 2009, 53(3), 40-45


[BioVT-2009-13]
Elisabeth Stammen, Stefan Böhm, Klaus Dilger, Cornelia Bähr, Jochen Büchs: Bonding glass - Withstanding the stresses of steam sterilisation. Adhäsion - Kleben & Dichten, 2009, 53(4), 28-32


[BioVT-2009-07]
David Ullisch, Jean L. Roberts, Wiltrud Treffenfeldt, Jochen Büchs: Investigation of the metabolism of Nicotiana tabacum (BY-2) cells using the Respiratory Monitoring System (RAMOS). In: In Vitro Biology Meeting , Charleston, USA, 06-10.06.2009


[BioVT-2008-11]
Amizon Azizan, Jochen Büchs: Effectiveness and measurement of liquid distribution in shake flask using fluorescence . Chemie Ingenieur Technik, 2008, 80(9), 1361-1362


[BioVT-2008-10]
Matthias Funke, A. Buchenauer, W. Mokwa, Frank Kensy, C. Müller, Jochen Büchs: Mikrofluidik meets BioLector - Die Mikrotiterplatte wird zum vollwertigen Fermenter . In: Dieter Beckmann, Manfred Meister (Eds.): Tagungsband - 14. Heiligenstädter Kolloquium


[BioVT-2008-08]
Kerasina Dimoula, Jochen Büchs, Antje Spieß: Enzymatic gas/solid reactions: an engineering approach.. In: 2nd International Conference ‘’Biocatalysis in non-conventional media’’, Moscow, Russia, 12-15.06.2008


[BioVT-2008-07]
Kerasina Dimoula, Jochen Büchs, Antje Spieß: Enzymatic gas/solid reactions: an engineering approach.. In: 7th European Symposium in Biochemical Engineering, Faro, Portugal, 07-10.09.2008


[BioVT-2007-14]
Rung-Kai Tan, Jochen Büchs: Measurement and Modeling of Mixing time in Shaking Bioreactors. Chemie Ingenieur Technik (CIT), 2007, 79(9), 1471


[BioVT-2007-12]
Amizon Azizan, T. Duarte, Cyril. P. Peter, Jochen Büchs: Gas-liquid Mass Transfer in Elevated Viscosity Medium with Corynebacterium glutamicum DM 1730 Culture Medium. Chemie Ingenieur Technik, 2007, 79(9), 1473


[BioVT-2006-13]
Frank Kensy, Jochen Büchs: On-line monitoring von Mikrofermentationen. Laborwelt, 2006, 7(1), 6-9


[BioVT-2005-06]
Jochen Büchs, Frank Kensy, Markus Jeude, Tibor Anderlei, Barbara Dittrich, Doris Klee: On-line monitoring and fed-batch operation in shake flask and micro titre plate cultures. Journal of Biotechnology, 2005, 118(2), 34-35


[BioVT-2004-14]
Werner Eberhard, J. Pinto, Jochen Büchs, G. Deerberg, Marion Ansorge-Schumacher: Bestimmung des Suspendierzustandes von Hydrogel-Kugeln in einem gerührten Reaktor. Chemie Ingenieur Technik, 2004, 76(9), 1253


[BioVT-2004-13]
A. Ramos Plasencia, Jochen Büchs, Wolfgang Marquardt: pO2-basierte Zufütterung zur Regelung der spezifischen Wachstumsrate in fed-batch Fermentationen. Chemie Ingenieur Technik, 2004, 76(9), 1236-1237


[BioVT-2004-05]
Jochen Büchs: Biochemical Engineering Journal - Preface. Biochem. Eng. J., 2004, 17(3), 153-153


[BioVT-2003-11]
Clara Ferloni, Matthias Heinemann, Th. Daußmann, Jochen Büchs: Enzymatic Gasphasenkatalyse zur Produktion chivaler Substanzen. transkript. BioTechnologie Nachrichten-Magazin, 2003


[BioVT-2002-05]
Clara Ferloni, W. Hummel, Jochen Büchs: Enzymatic reaction in the gaseous phase. Chemie Ingenieur Technik, 2002, 74(5), 659


[BioVT-2002-04]
Christoph Stöckmann, Mario Losen, Ulrike Dahlems, Gerd Gellissen, Jochen Büchs: Definition of reproducible screening conditions case sample Hansenula polymorpha. Chemie Ingenieur Technik, 2002, 74(5), 701


[BioVT-2002-03]
Matthias Heinemann, B. Doumeche, Marion B. Ansorge-Schumacker, Jochen Büchs: Gel-immobilized enzymes for the production of hydrophobic substances - modeling and process optimization. Chemie Ingenieur Technik, 2002, 74(5), 555-556


[BioVT-2001-10]
Jochen Büchs, Tibor Anderlei: RAMOS, Online-Messung der Atmungsaktivitäten biologischer Kulturen in geschüttelten Bioreaktoren. BIOforum, 2001, 3, 149-151


[BioVT-1999-02]
Tibor Anderlei, Jochen Büchs: Online-Ermittlung der Sauerstofftransferrate von mikrobiellen Kulturen im Schüttelkolben. BIOforum, 1999, 4, 182-186


[BioVT-1998-01]
R. Klingelhöfer, D. Preis, B. Roth, B. Maier, Jochen Büchs: Entwicklung und Optimierung eines kontinuierlichen kaskadierbaren Bioreaktorsystems im Kleinmaßstab. Chemie Ingenieur Technik, 1998, 70(9), 1124


[BioVT-1996-01]
Jochen Büchs, C. Milbradt, B. Zoels: Dimensionslose Beschreibung des spezifischen Leistungseintrags in schikanelosen Schüttelkolben. Chemie Ingenieur Technik, 1996, 68(9), 1168-1168


[BioVT-1995-01]
Jochen Büchs, H. Kramm, B. Mayer, B. Zoels: Der Leistungseintrag zur Charakterisierung und Maßstabübertragung von Bioprozessen aus Schüttelkolben. Chemie Ingenieur Technik, 1995, 67(9), 1111-1112


[BioVT-1994-01]
Jochen Büchs, D. Hillmann: Neue Methode zum quantitativen Vergleich der Dispergierintensität in verschiedenen Reaktoren. Chemie Ingenieur Technik, 1994, 66(9), 1187


[BioVT-1991-02]
Jochen Büchs: Kopplung von Reaktions- und Kostenmodell: Der Weg zur effizienten Prozessoptimierung. Chemie Ingenieur Technik, 1991, 63(2), 89-98



Patente



[BioVT-2006-14]
Jochen Büchs, Mokwa W, Schnakenberg U, Kensy F, Müller C, Klammer I., Buchenauer A, Hofmann M: Vorrichtung und Verfahren zur Zu- und Abfuhr von Fluiden in geschüttelten Mikroreaktoren Arrays. German patent application 29.6.2006,


[BioVT-2005-12]
Jochen Büchs, Jeude M, Klee D, Dittrich B: Fed-batch Microwellplatte (FEB-MWP). German patent application 18.5.2005, DE 10 2005 022 045.2


[BioVT-2004-12]
Jochen Büchs, Kensy F, Samorski M: Verfahren und Vorrichtung zur Erfassung von Prozeßparametern von Reaktionsflüssigkeiten in mehreren geschüttelten Mikroreaktoren. German patent application 2.4.2004, DE 10 2004 017 039.8


[BioVT-2003-10]
Kleen A, Sättler A, Jochen Büchs, Akgün A, Stöckmann Ch: Low copper fermentation media for the manufacture of phenol oxidases with filamentous fungi,. PCT Int. Appl. 2003, WO 0308568


[BioVT-2002-07]
Wack H, Deerberg G, Bergstedt U, Jochen Büchs, Heinemann M, Ansorge-Schumacher M: Integrierte Immobilisat-Aufbereitung. German patent application 22.2.2002, Aktenzeichen 102 07 557.3-41


[BioVT-2002-06]
Grohmann K, Jansen J, Jochen Büchs: Mechanical shaker and fermentation installation. PCT Int. Appl. 2002, WO 0101000


[BioVT-2000-04]
Jochen Büchs, Maier H.-R, Aneziris Ch: Immobilisierung von aeroben Mikroorganismen mittels Trägermaterialmonolithen mit Makrokanälen, Mikrokanälen und Besiedlungsräumen. German patent application 22. 3. 2000, Aktenzeichen DE 100 14 016 A1


[BioVT-1998-02]
Jochen Büchs, Maier B, Roth B: Kontinuierliches, kaskadierbares Schüttelbioreaktorsystem. European patent application 29. 9. 1998, Aktenzeichen EP 99041 kr


[BioVT-1997-01]
Jochen Büchs, Anderlei T: Verfahren und Vorrichtung zur Ermittlung und Überwachung des physiologischen Zustands mikrobieller Kulturen. European patent application 1. 9. 1997, Aktenzeichen EP 98008 kr


[BioVT-1993-01]
Jochen Büchs, Kramm H: Automatisches Meßsystem zur sterilen online Bestimmung der Sauerstofftransferrate (OTR) in Schüttelkolben. German patent application 12. 5. 1993, Aktenzeichen P 44 15 444.5


[BioVT-1988-04]
Jochen Büchs, Wandrey Ch, Kula M.-R., Radke M: Inorganic carrier with an amine-containing surface layer for the immobilization of microorganisms or cells, process for its production and use thereof. EPA 88.113035.5 (11.08.1988), US 228,66 (05.08.1988)


[BioVT-1987-01]
Jochen Büchs, Wandrey Ch, Radke M.: Trägerkörper zur Immobilisierung von Zellen oder Mikroorganismen aus anorganischem Material mit basischer aminhaltiger Oberflächenbeschichtung,. German patent application 13. 8. 1987, P 37 26 942.0-41, 1987


[BioVT-1984-01]
Jochen Büchs, Endo I., Inoue I., Furusaki S, Benno Y., Nagamune T: Seikin-su sokutei-hoho oyobi sono sochi. Japanese patent application, Priority 18. June 1984



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Bioverfahrenstechnik
Prof. Dr.-Ing. Büchs


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Prof. Dr.-Ing. Marquardt


Chemische Verfahrenstechnik
Prof. Dr.-Ing. Wessling


Mechanische Verfahrenstechnik
Prof. Dr.-Ing. Modigell


Thermische Verfahrenstechnik
kommissarische Leitung Prof. Dr.-Ing. Spieß


Enzymprozesstechnik
Prof. Dr.-Ing. Spieß


Systemverfahrenstechnik
Prof.Alexander Mitsos, Ph.D.


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