Biochemical Engineering
Prof. Dr.-Ing. Jochen Büchs

Our research activities are mainly focused on new methods and devices for the development of advanced biotechnological production processes. This requires a combination of theoretical knowledge in biology and engineering and experience in the design and realisation of experimental investigations. Our group sustains close co-operations with several reputable companies and provides practical solutions to complex biotechnological problems. more


Our focus on research:

Model-based experimental analysis
Tailor-Made Fuels from Biomass (TMFB)
Shaken bioreactors
Fermentation technology
Biocatalysis
Online measurement techniques

Our current projects:

    Model-based experimental analysis

    • Development of a measurement technique for an online detection of recombinant proteins with short tags in microtiter plates more

    Shaken bioreactors

    • CoMoFarm - Contained Molecular Farming – Controllable Contained Systems for High Yield and Consistency more
    • Smart Dosing - Diffusive hydrogel controlled substrate dosing in microbioreactors to increase the efficiency in bioprocess development more
    • Influence of recombinant enzyme on host cell metabolic activity and expression more
    • Development of new technique for autoclavable glass bonding more
    • Development of a defined medium for the fermentation of technical enzymes, proteins and peptides with Bacillus licheniformis more
    • Development and Characterisation of a Dialysis Fed-batch Shake Flask more
    • Advanced Process Engineering of Acetic Acid Bacteria more
    • Industrial collaboration; Technical characterization of small scale cultivation vessels for a defined scaling more
    • Tailoring selectivity of whole cell biotransformations by organic solvents more

    Fermentation technology

    • Direct Fermentation of Green Energy Plants to Platform Chemicals more
    • MoBiDiK - Modular Bioproduction - Disposable and Continouous more

    Biocatalysis

    • Automated screening system for rational selection and characterization of most efficient biocatalysts and process parameters. more

    Online measurement techniques

    • Analysis and control of bio processes in a continuously controlled calorimetric fermenter system more
    • Development of a method for high-precision on-line monitoring of respiration activities in small scale cultures more
    • Development of a measurement technique for an online detection of recombinant proteins with short tags in microtiter plates more
    • OptoSys - New optical sensors und photo-regulators for light-mediated control and analysis of molecular systems more