Model-based experimental analysis (MEXA)
Many not (sufficiently well) understood processes play a major role in chemical engineering processes. Such processes, as for instance multi-phase reactions, absorption, extraction and rectification, can thus not be quantified in a reasonably accurate manner. In order to achieve a more accurate prediction of the kinetics of such processes, a sound understanding of the underlying kinetic phenomena is necessary.
The MEXA methodology, developed within the CRC 540, aims at achieving a detailed understanding of these kinetic phenomena and their interactions, represented in form of mechanistic mathematical models. Only based on such sound models, a rational product- and process design becomes feasible. This is especially true for currently not sufficiently well understood chemical processes based on biomass, as for instance in the cluster of excellence “Tailor Made Fuels from Biomass”.
A mechanistic modeling of such complex systems can only be achieved if theorists and experimenters closely collaborate, combining high resolution measurement techniques and systems-theory knowledge. Therefore, the AVT promotes the development and validation of new methods that will generate the results in small scale, but can easily be transferred to production scale. This mesoscale-view is only made possible by a lot of novel innovative approaches.
Current research focus in the thematic area: Model-based experimental analysis (MEXA)
![]() | Dynamic Real-time Optimization / Model-based Process Control |
![]() | Model-based experimental analysis |
![]() | Membrane technology |
![]() | Extraction |
![]() | Tailor-Made Fuels from Biomass (TMFB) |
![]() | Online measurement techniques |
Our current projects:
Dynamic Real-time Optimization / Model-based Process Control
- Autoprofit - Advanced Autonomous Model-Based Operation of Industrial Process Systems more
Model-based experimental analysis
- Design of extractors for phytoextraction more
- Determination of concentration and temperature-dependent diffusion coefficients in hydrogels using Raman spectroscopy more
- Development of a measurement technique for an online detection of recombinant proteins with short tags in microtiter plates more
- Formulation and solution of three-dimensional inverse heat transfer problems in pool boiling more
- Identification of complex multiphase reaction systems more
- Incremental Identification of Transport Phenomena in Laminar Wavy Falling Films more
- Integrated product and process design for novel biofuels more
- Modelling and identification of first principles dynamic process models for predictive control and real-time optimization more
- Multimod: Mexa for hybrid models more
- Multimod: MEXA for solvent selection more
- Systems biology of IL-6 induced signal transduction more
- Boostfund-Projekt OP - The role of electrical effects across biological membranes. more
- Polyelectrolyte multilayers on soft and porous substrates more
- Design of extractors for phytoextraction more
Tailor-Made Fuels from Biomass (TMFB)
- Integrated product and process design for novel biofuels more
- Analysis and control of bio processes in a continuously controlled calorimetric fermenter system more
- Development of a method for high-precision on-line monitoring of respiration activities in small scale cultures more
- Development of a measurement technique for an online detection of recombinant proteins with short tags in microtiter plates more
- Mass Transfer in Falling Liquid Films more









