[Fachzeitschriftenartikel]
Halmschlag, Birthe; Hoffmann, Kyra; Hanke, René; Putri, Sastia P.; Fukusaki, Eiichiro; Büchs, Jochen; Blank, Lars M.
Comparison of Isomerase and Weimberg Pathway for γ-PGA Production From Xylose by Engineered Bacillus subtilis
In: Frontiers in Bioengineering and Biotechnology, 7, 476, 2020
[DOI: 10.3389/fbioe.2019.00476]

[Fachzeitschriftenartikel]
Heyman, Benedikt; Tulke, Hannah; Putri, Sastia Prama; Fukusaki, Eiichiro; Büchs, Jochen
Online monitoring of the respiratory quotient reveals metabolic phases during microaerobic 2,3-butanediol production with Bacillus licheniformis
In: Advanced science, 20 (3/4), 133-144, 2019
[DOI: 10.1002/elsc.201900121]

[Fachzeitschriftenartikel]
Stoffels, Peter; Müller, Markus Jan; Stachurski, Sarah; Terfrüchte, Marius; Schröder, Sebastian; Ihling, Nina; Wierckx, Nick; Feldbrügge, Michael; Schipper, Kerstin; Büchs, Jochen
Complementing the intrinsic repertoire of Ustilago maydis for degradation of the pectin backbone polygalacturonic acid
In: Journal of biotechnology, 307, 148-163, 2019
[DOI: 10.1016/j.jbiotec.2019.10.022]

[Patent]
Schillheim, Britta; Büchs, Jochen; Conrath, Uwe; Schilling, Jana Viola
Method for identifying substances which prime a defense response
, 2020

[Fachzeitschriftenartikel]
Westerwalbesloh, Christoph; Brehl, Carl; Weber, Sophie; Probst, Christopher; Widzgowski, Janka; Grünberger, Alexander; Pfaff, Christian; Nedbal, Ladislav; Kohlheyer, Dietrich
A microfluidic photobioreactor for simultaneous observation and cultivation of single microalgal cells or cell aggregates
In: PLOS ONE, 14 (4), e0216093, 2019
[DOI: 10.1371/journal.pone.0216093]

[Doktorarbeit]
Heyman, Benedikt
Online monitoring-based methodologies to assess microaerobic 2,3-Butanediol production
, 2019
[DOI: 10.18154/RWTH-2020-03421]

[Fachzeitschriftenartikel]
Rockenbach, Alexander Benjamin; Sudarsan, Suresh; Berens, Judith; Kosubek, Michael; Lazar, Jaroslav; Demling, Philipp; Hanke, René; Mennicken, Philip; Ebert, Birgitta Elisabeth; Blank, Lars M.; Schnakenberg, Uwe
Microfluidic Irreversible Electroporation—A Versatile Tool to Extract Intracellular Contents of Bacteria and Yeast
In: Metabolites : open access journal, 9 (10), 211, 2019
[DOI: 10.3390/metabo9100211]

[Doktorarbeit]
Kunze, Martin
Automated high-throughput experimentation for a fast and reliable bioprocess development
, 2019
[DOI: 10.18154/RWTH-2020-01375]

[Fachzeitschriftenartikel]
Lara, Alvaro R.; Jaén, Karim E.; Folarin, Olusegun; Keshavarz-Moore, Eli; Büchs, Jochen
Effect of the oxygen transfer rate on oxygen-limited production of plasmid DNA by Escherichia coli
In: Biochemical engineering journal, 150, 107303, 2019
[DOI: 10.1016/j.bej.2019.107303]

[Fachzeitschriftenartikel]
Ihling, Nina; Uhde, Andreas; Scholz, Romy; Schwarz, Christian; Schmitt, Lutz; Büchs, Jochen
Scale-up of a Type I secretion system in E. coli using a defined mineral medium
In: Biotechnology progress, 36 (2), e2911, 2019
[DOI: 10.1002/btpr.2911]

[Fachzeitschriftenartikel]
Keil, Timm; Landenberger, Markus; Dittrich, Barbara; Selzer, Sebastian; Büchs, Jochen
Precultures Grown under Fed-Batch Conditions Increase the Reliability and Reproducibility of High-Throughput Screening Results
In: Biotechnology journal : BTJ, 14 (11), 1800727, 2019
[DOI: 10.1002/biot.201800727]

[Fachzeitschriftenartikel]
Kont, Riin; Pihlajaniemi, Ville; Borisova, Anna S.; Aro, Nina; Marjamaa, Kaisa; Loogen, Judith; Büchs, Jochen; Eijsink, Vincent G. H.; Kruus, Kristiina; Väljamäe, Priit
The liquid fraction from hydrothermal pretreatment of wheat straw provides lytic polysaccharide monooxygenases with both electrons and H2O2 co-substrate
In: Biotechnology for biofuels, 12 (1), 235, 2019
[DOI: 10.1186/s13068-019-1578-5]

[Doktorarbeit]
Müller, Markus Jan
Online analytics of pectic compound degradation in small-scale using $\textit Ustilago Maydis$
, 2019
[DOI: 10.18154/RWTH-2019-11736]

[Fachzeitschriftenartikel]
Ladner, Tobias Michael David; Flitsch, David Matthias; Lukacs, Mihaly; Sieben, Michaela Maria; Büchs, Jochen
Combined dissolved oxygen tension and online viscosity measurements in shake flask cultivations via infrared fluorescent oxygen‐sensitive nanoparticles
In: Biotechnology & bioengineering, 116 (12), 3215-3227, 2019
[DOI: 10.1002/bit.27145]

[Fachzeitschriftenartikel]
Tesche, Sebastian; Rösemeier‐Scheumann, René; Lohr, Jonas; Hanke, René; Büchs, Jochen; Krull, Rainer
Salt‐enhanced cultivation as a morphology engineering tool for filamentous actinomycetes: Increased production of labyrinthopeptin A1 in Actinomadura namibiensis
In: Engineering in life sciences, 19, 781-794, 2019
[DOI: 10.1002/elsc.201900036]

[Fachzeitschriftenartikel]
binti Azizan, Amizon; Sieben, Michaela Maria; Wandrey, Georg Benjamin; Büchs, Jochen
Reassessing the out‐of‐phase phenomenon in shake flasks by evaluating the angle‐dependent liquid distribution relative to the direction of the centrifugal acceleration
In: Biotechnology & bioengineering, 116 (11), 2983-2995, 2019
[DOI: 10.1002/bit.27132]

[Fachzeitschriftenartikel]
Müller, Janina; Hütterott, Anne; Habicher, Tobias; Mußmann, Nina; Büchs, Jochen
Validation of the transferability of membrane-based fed-batch shake flask cultivations to stirred-tank reactor using three different protease producing Bacillus strains
In: Journal of bioscience and bioengineering, 128 (5), 599-605, 2019
[DOI: 10.1016/j.jbiosc.2019.05.003]

[Abstract, Beitrag zu einem Tagungsband, Fachzeitschriftenartikel]
Kauffmann, Kira; Brendt, Julia; Schiwy, Andreas Herbert; Hollert, Henner; Büchs, Jochen
Online Monitoring of Respiration Activity Allows for an Optimized Ames Mutagenicity Test
In: Environmental and molecular mutagenesis, 60 (S1), P93, 2019

[Doktorarbeit]
Lamm, Robin
Process monitoring and characterization to control the production of active inclusion bodies applying high-throughput technologies
, 2019

[Fachzeitschriftenartikel]
Habicher, Tobias; Czotscher, Vroni; Klein, Tobias; Daub, Andreas; Keil, Timm; Büchs, Jochen
Glucose‐containing polymer rings enable fed‐batch operation in microtiter plates with parallel online measurement of scattered light, fluorescence, dissolved oxygen tension, and pH
In: Biotechnology & bioengineering, 116, 2250-2262, 2019
[DOI: 10.1002/bit.27077]

[Fachzeitschriftenartikel]
Keil, Timm; Dittrich, Barbara; Rührer, J.; Morschett, Holger; Lattermann, Clemens; Möller, M.; Büchs, Jochen
Polymer-based ammonium-limited fed-batch cultivation in shake flasks improves lipid productivity of the microalga Chlorella vulgaris
In: Bioresource technology, 291, 121821, 2019
[DOI: 10.1016/j.biortech.2019.121821]

[Konferenzbeitrag]
Wollborn, David; Müller, Rebecca Luise; Germer, Andrea; Blank, Lars M.; Büchs, Jochen
Small scale cultivation strategy ensuring the optimal induction time point for individual Komagataella phaffii clones during primary screening
In: Recombinant Protein Production Hersonissos 2019-04-24 - 2019-04-27, 2019

[Fachzeitschriftenartikel]
Sieben, Michaela Maria; Hanke, René; Büchs, Jochen
Contact-free determination of viscosity in multiple parallel samples
In: Scientific reports, 9, 8335, 2019
[DOI: 10.1038/s41598-019-44859-z]

[Fachzeitschriftenartikel]
Heyman, Benedikt; Lamm, Robin; Tulke, Hannah; Regestein, Lars; Büchs, Jochen
Shake flask methodology for assessing the influence of the maximum oxygen transfer capacity on 2,3-butanediol production
In: Microbial cell factories, 18, 78, 2019
[DOI: 10.1186/s12934-019-1126-9]

[Preprint]
Nies, Salome; Dinger, Robert; Chen, Yan; Wordofa, Gossa G.; Kristensen, Mette; Schneider, Konstantin; Büchs, Jochen; Petzold, Christopher J.; Keasling, Jay D.; Blank, Lars M.; Ebert, Birgitta Elisabeth
The metabolic response of Pseudomonas taiwanensis to NADH dehydrogenase deficiency
, 2019
[DOI: 10.1101/624536]

[Doktorarbeit]
Herweg, Elena Ruth
Characterization of Gluconobacter oxydans strains and development of a production process for 5-Ketofructose
, 2019
[DOI: 10.18154/RWTH-2019-02770]

[Fachzeitschriftenartikel]
Habicher, Tobias; John, Arian; Scholl, Niklas; Daub, Andreas; Klein, Tobias; Philip, Priya; Büchs, Jochen
Introducing substrate limitations to overcome catabolite repression in a protease producing Bacillus licheniformis strain using membrane‐based fed‐batch shake flasks
In: Biotechnology and Bioengineering, 116 (5), 1326-1340, 2019
[DOI: 10.1002/bit.26948]

[Fachzeitschriftenartikel]
Keil, Timm; Dittrich, Barbara; Lattermann, Clemens; Habicher, Tobias; Büchs, Jochen
Polymer-based controlled-release fed-batch microtiter plate - diminishing the gap between early process development and production conditions
In: Journal of biological engineering : jbe, 13 (1), 18, 2019
[DOI: 10.1186/s13036-019-0147-6]

[Poster]
Stachurski, Sarah; Büchs, Jochen; Gómez, Elsa; Peña, Carlos
Production of Alginate with Azotobacter vinelandii
In: BioProcessingDays 2019 Recklinghausen 2019-02-18 - 2019-02-20, 2019

[Fachzeitschriftenartikel]
Eggert, Armin; Maßmann, Tim; Kreyenschulte, Dirk Herbert; Becker, Moritz Michael; Heyman, Benedikt; Büchs, Jochen; Jupke, Andreas
Integrated in-situ product removal process concept for itaconic acid by reactive extraction, pH-shift back extraction and purification by pH-shift crystallization
In: Separation and purification technology, 215, 463-472, 2019
[DOI: 10.1016/j.seppur.2019.01.011]

[Doktorarbeit]
binti Azizan, Amizon
Optical measurement and assessment of liquid distribution in shake flasks
, 2018
[DOI: 10.18154/RWTH-2019-05667]

[Doktorarbeit]
Ihling, Nina
Characterization of a type I secretion system in E. coli by online monitoring of the respiration activity
, 2018

[Doktorarbeit]
Mühlmann, Martina Julia
Robotic high-throughput screening for the optimization and prediction of recombinant protein expression in microscale
, 2018
[DOI: 10.18154/RWTH-2019-00834]

[Fachzeitschriftenartikel]
Mühlmann, Martina Julia; Forsten, Eva Christine; Noack, Saskia; Büchs, Jochen
Prediction of Recombinant Protein Production by Escherichia coli Derived OnlineFrom Indicators of Metabolic Burden
In: Biotechnology progress, 34 (6), 1543-1552, 2018
[DOI: 10.1002/btpr.2704]

[Fachzeitschriftenartikel]
Müller, Markus Jan; Stachurski, Sarah; Stoffels, Peter; Schipper, Kerstin; Feldbrügge, Michael; Büchs, Jochen
Online evaluation of the metabolic activity of Ustilago maydis on (poly)galacturonic acid
In: Journal of biological engineering : jbe, 12 (34), 17, 2018
[DOI: 10.1186/s13036-018-0128-1]

[Fachzeitschriftenartikel]
Bär, Janosch; Phongpreecha, Thanaphong; Singh, Sandip Kumar; Kral Yilmaz, Melisa; Foster, Cliff E.; Crowe, Jacob D.; Hodge, David B.
Deconstruction of hybrid poplar to monomeric sugars and aromatics using ethanol organosolv fractionation
In: Biomass Conversion and Biorefinery, 8 (4), 813-824, 2018
[DOI: 10.1007/s13399-018-0330-x]

[Fachzeitschriftenartikel]
Gamboa-Suasnavart, Ramsés A.; Valdez-Cruz, Norma A.; Gaytan-Ortega, Gerardo; Reynoso-Cereceda, Greta I.; Cabrera-Santos, Daniel; López-Griego, Lorena; Klöckner, Wolf; Büchs, Jochen; Trujillo-Roldán, Mauricio A.
The metabolic switch can be activated in a recombinant strain of Streptomyces lividans by a low oxygen transfer rate in shake flasks
In: Microbial cell factories, 17 (1), 189, 2018
[DOI: 10.1186/s12934-018-1035-3]

[Fachzeitschriftenartikel]
Hartmann, Sandra K.; Stockdreher, Yvonne; Wandrey, Georg Benjamin; Hosseinpour Tehrani, Hamed; Zambanini, Thiemo; Meyer, Andreas; Büchs, Jochen; Blank, Lars M.; Schwarzländer, Markus; Wierckx, Nick
Online in vivo monitoring of cytosolic NAD redox dynamics in Ustilago maydis
In: Biochimica et biophysica acta / Bioenergetics, 1859 (10), 1015-1024, 2018
[DOI: 10.1016/j.bbabio.2018.05.012]

[Fachzeitschriftenartikel]
Terfrüchte, Marius; Wewetzer, Sandra J.; Sarkari, Parveen; Stollewerk, Daniel; Franz-Wachtel, Mirita; Macek, Boris; Schlepütz, Tino; Feldbrügge, Michael; Büchs, Jochen; Schipper, Kerstin
Tackling destructive proteolysis of unconventionally secreted heterologous proteins in Ustilago maydis
In: Journal of biotechnology, 284, 37-51, 2018
[DOI: 10.1016/j.jbiotec.2018.07.035]

[Doktorarbeit]
Philip, Evangeline Priya
Optimization of the membrane-based fed-batch shake flask for E. coli cultivations
, 2018

[Konferenzbeitrag]
Keil, Timm; Büchs, Jochen
Fed-batch microtiter plate - Diminishing the gap between early process development and production conditions
In: ProcessNet-Jahrestagung und 33. DECHEMA-Jahrestagung der Biotechnologen 2018 Aachen 2018-09-10 - 2018-10-13, 2018

[Konferenzbeitrag]
Kauffmann, Kira; Brendt, Julia; Schiwy, Andreas Herbert; Hollert, Henner; Büchs, Jochen
Online monitoring of respiration activity helps characterizing and optimizing the Ames mutagenicity test
In: European Society of Biochemical Engineering Sciences Lissabon 2018-09-09 - 2018-09-12, 2018

[Konferenzbeitrag]
Habicher, Tobias
Carbon- and nitrogen-limited cultivation of a protease-producing Bacillus licheniformis using membrane-based fed-batch shake flasks
In: 12th Symposium on Biochemical Engineering Sciences Lissabon 2018-09-09 - 2018-09-12, 2018

[Doktorarbeit]
Lattermann, Clemens
Characterization and simulation of substrate release in a novel 48-well fed-batch microtiter plate
, 2018
[DOI: 10.18154/RWTH-2018-229571]

[Fachzeitschriftenartikel]
Regestein, Lars; Klement, Tobias; Grande, Philipp M.; Kreyenschulte, Dirk Herbert; Heyman, Benedikt; Maßmann, Tim; Eggert, Armin; Keller, Robert Gregor; Wang, Yumei; Wierckx, Nick; Blank, Lars M.; Spiess, Antje C.; Leitner, Walter; Bolm, Carsten; Wessling, Matthias; Jupke, Andreas; Agler-Rosenbaum, Miriam; Büchs, Jochen
From beech wood to itaconic acid: case study on biorefinery process integration
In: Biotechnology for biofuels, 11 (1), 279-289, 2018
[DOI: 10.1186/s13068-018-1273-y]

[Fachzeitschriftenartikel]
Jäger, Vera D.; Lamm, Robin; Kloß, Ramona; Kaganovitch, Eugen; Grünberger, Alexander; Pohl, Martina; Büchs, Jochen; Jaeger, Karl-Erich; Krauss, Ulrich
A Synthetic Reaction Cascade Implemented by Colocalization of Two Proteins within Catalytically Active Inclusion Bodies
In: ACS synthetic biology, 7 (9), 2282-2295, 2018
[DOI: 10.1021/acssynbio.8b00274]

[Konferenzbeitrag]
Keil, Timm; Dittrich, B.; Büchs, Jochen
Application of a fed-batch microtiter plate to overcome hurdles in the early steps of process development
In: ProcessNet-Jahrestagung und 33. Dechema Jahrestagung der Biotechnologen Aachen 2018-09-10 - 2018-09-13, 2018

[Abstract, Beitrag zu einem Tagungsband, Fachzeitschriftenartikel]
Keil, Timm; Dittrich, Barbara; Büchs, Jochen
Application of a fed-batch microtiter plate to overcome hurdles in the early steps of process development
In: Chemie - Ingenieur - Technik, 90 (9), V6.43, 2018
[DOI: 10.1002/cite.201855299]

[Abstract, Beitrag zu einem Tagungsband, Fachzeitschriftenartikel]
Flake, Carsten; Brands, Thorsten; Koß, Hans-Jürgen; Dinger, Robert; Bardow, André
Nicht-invasive Inline-Analyse von Bioprozessen mit Raman-Spektroskopie und Indirect Hard Modeling (IHM)
In: Chemie - Ingenieur - Technik : CIT, 90 (9), P6.11, 2018
[DOI: 10.1002/cite.201855314]

[Beitrag zu einem Tagungsband]
Müller, Markus Jan; Stoffels, Peter; von Helden, Elena; Schipper, Kerstin; Wierckx, Nick; Feldbrügge, Michael; Blank, Lars M.; Büchs, Jochen
Online determination of the metabolic and enzymatic activity of Ustilago maydis on pectic substrates
In: [14th International Conference on Renewable Resources and Biorefineries, RRB-14, 2018-05-30 - 2018-06-01, Ghent, Belgium], 2018