Wolfgang Wiechert

Person

Prof. Dr. rer. nat.

Wolfgang Wiechert

Universitätsprofessor
Computational Systems Biotechnology

Professorship

Address

FZ Jülich GmbH, IBG-1

52425 Jülich

Contact

WorkPhone
Phone: +49 2461 615557
 

Resume

More informationen about Wolfgang Wiechert you can find here

Publications

Citations in Google Scholar

Researchgate

 

Publications

Titel Author(s)
Introducing molasses as an alternative feedstock into itaconate production using Ustilago sp
Erschienen in: New biotechnology (2023)
Helm, Tabea
Niehoff, Paul-Joachim
Gätgens, Jochem
Stausberg, Thilo
Pichler, Bernadette
Häßler, Thomas
Wiechert, Wolfgang
Büchs, Jochen
Wierckx, Nick
Noack, Stephan (Corresponding author)
Explore or exploit? A model-based screening strategy for PETase secretion by Corynebacterium glutamicum
Erschienen in: Biotechnology and bioengineering (2022)
Helleckes, Laura Marie
Müller, Carolin
Griesbach, Tim
Waffenschmidt, Vera
Moch, Matthias
Osthege, Michael
Wiechert, Wolfgang
Oldiges, Marco (Corresponding author)
From Microbial Succinic Acid Production to Polybutylene Bio-Succinate Synthesis 
Erschienen in: Chemie - Ingenieur - Technik : CIT (2023)
Tenhaef, Niklas
Hermann, Alina
Müller, Moritz Fabian
Görtz, Jonas
Marienhagen, Jan
Oldiges, Marco
Wiechert, Wolfgang
Bott, Michael
Jupke, Andreas
Hartmann, Laura
Herres-Pawlis, Sonja
Noack, Stephan (Corresponding author)
Automated Characterization of Catalytically Active Inclusion Body Production in Biotechnological Screening Systems
Erschienen in: 44th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) / pre-conference workshops & social events: Monday, July 11, 2022, conference dates: Tuesday, July 12-Friday, July 15, 2022 / conference chair: Christopher James (University of Warwick), conference co-chair: James Patton (University of Chicago) ; programm chair: Ron Summers (Collegium Basilea) (2022)
Ruzaeva, Karina (Corresponding author)
Küsters, Kira (Corresponding author)
Wiechert, Wolfgang
Berkels, Benjamin
Oldiges, Marco
Noh, Katharina
Control of parallelized bioreactors II: probabilistic quantification of carboxylic acid reductase activity for bioprocess optimization
Erschienen in: Bioprocess and biosystems engineering (2022)
von den Eichen, Nikolas (Corresponding author)
Osthege, Michael
Dölle, Michaela
Bromig, Lukas
Wiechert, Wolfgang
Oldiges, Marco
Weuster-Botz, Dirk
CellSium: versatile cell simulator for microcolony ground truth generation
Erschienen in: Bioinformatics advances (2022)
Sachs, Christian Carsten
Ruzaeva, Karina
Seiffarth, Johannes
Wiechert, Wolfgang
Berkels, Benjamin
Nöh, Katharina (Corresponding author)
Communities of Niche-optimized Strains (CoNoS) : Design and creation of stable, genome-reduced co-cultures
Erschienen in: Metabolic engineering (2022)
Schito, Simone
Zuchowski, Rico
Bergen, Daniel
Strohmeier, Daniel
Wollenhaupt, Bastian
Menke, Philipp
Seiffarth, Johannes
Nöh, Katharina
Kohlheyer, Dietrich
Bott, Michael
Wiechert, Wolfgang
Baumgart, Meike
Noack, Stephan (Corresponding author)
Accelerated strain construction and characterization of C. glutamicum protein secretion by laboratory automation
Erschienen in: Applied microbiology and biotechnology (2022)
Müller, Carolin C.
Bakkes, Patrick J.
Lenz, Patrick
Waffenschmidt, Vera
Helleckes, Laura Marie
Jaeger, Karl-Erich
Wiechert, Wolfgang
Knapp, Andreas
Freudl, Roland
Oldiges, Marco (Corresponding author)
Construction and characterization of BsGDH-CatIB variants and application as robust and highly active redox cofactor regeneration module for biocatalysis
Erschienen in: Microbial cell factories (2022)
Küsters, Kira
Saborowski, Ronja
Wagner, Christian
Hamel, Rebecca
Spöring, Jan-Dirk
Wiechert, Wolfgang
Oldiges, Marco (Corresponding author)
Hot isopropanol quenching procedure for automated microtiter plate scale 13C-labeling experiments
Erschienen in: Microbial cell factories (2022)
Nießer, Jochen
Müller, Moritz Fabian
Kappelmann, Jannick
Wiechert, Wolfgang
Noack, Stephan (Corresponding author)
Bayesian calibration, process modeling and uncertainty quantification in biotechnology
Erschienen in: PLoS Computational Biology (2022)
Helleckes, Laura Marie
Osthege, Michael
Wiechert, Wolfgang
von Lieres und Wilkau, Eric
Oldiges, Marco (Corresponding author)
Toward the Sustainable Production of the Active Pharmaceutical Ingredient Metaraminol
Erschienen in: ACS sustainable chemistry & engineering (2022)
Labib, Mohamed
Grabowski, Laura
Brüsseler, Christian
Kallscheuer, Nicolai
Wachtendonk, Luisa
Fuchs, Thomas Leonard
Jupke, Andreas
Wiechert, Wolfgang
Marienhagen, Jan
Rother, Dörte
Noack, Stephan (Corresponding author)
Metabolic Footprinting of Microbial Systems Based on Comprehensive In Silico Predictions of MS/MS Relevant Data
Erschienen in: Metabolites : open access journal (2022)
Reiter, Alexander
Asgari, Jian
Wiechert, Wolfgang
Oldiges, Marco (Corresponding author)
bletl : A Python package for integrating BioLector microcultivation devices in the Design-Build-Test-Learn cycle
Erschienen in: Engineering in life sciences (2022)
Osthege, Michael
Tenhaef, Niklas
Zyla, Rebecca
Müller, Carolin
Hemmerich, Johannes
Wiechert, Wolfgang
Noack, Stephan
Oldiges, Marco (Corresponding author)
Comprehensive Analysis of C. glutamicum Anaplerotic Deletion Mutants Under Defined d-Glucose Conditions
Erschienen in: Frontiers in Bioengineering and Biotechnology (2021)
Kappelmann, Jannick
Klein, Bianca
Papenfuß, Mathias
Lange, Julian
Blombach, Bastian
Takors, Ralf
Wiechert, Wolfgang
Polen, Tino
Noack, Stephan (Corresponding author)
A fully automated pipeline for the dynamic at‐line morphology analysis of microscale Aspergillus cultivation
Erschienen in: Fungal Biology and Biotechnology (2021)
Jansen, Roman
Küsters, Kira
Morschett, Holger
Wiechert, Wolfgang
Oldiges, Marco (Corresponding author)
High-Quality Genome-Scale Reconstruction of Corynebacterium glutamicum ATCC 13032
Erschienen in: Frontiers in microbiology (2021)
Feierabend, Martina
Renz, Alina
Zelle, Elisabeth
Nöh, Katharina
Wiechert, Wolfgang
Dräger, Andreas (Corresponding author)
Scaling production of GFP1-10 detector protein in E. coli for secretion screening by split GFP assay
Erschienen in: Microbial cell factories (2021)
Müller, Carolin C.
Igwe, Chika L.
Wiechert, Wolfgang
Oldiges, Marco (Corresponding author)
Microaerobic growth-decoupled production of α-ketoglutarate and succinate from xylose in a one-pot process using Corynebacterium glutamicum
Erschienen in: Biotechnology journal : BTJ (2021)
Tenhaef, Niklas
Kappelmann, Jannick
Eich, Arabel
Weiske, Marc
Brieß, Lisette
Brüsseler, Christian
Marienhagen, Jan
Wiechert, Wolfgang
Noack, Stephan (Corresponding author)
Robotic integration enables autonomous operation of laboratory scale stirred tank bioreactors with model-driven process analysis
Erschienen in: Biotechnology & bioengineering (2021)
Morschett, Holger
Tenhaef, Niklas
Hemmerich, Johannes
Herbst, Laura Marie
Spiertz, Markus
Dogan, Deniz
Wiechert, Wolfgang
Noack, Stephan
Oldiges, Marco (Corresponding author)
An energetic profile of Corynebacterium glutamicum underpinned by measured biomass yield on ATP
Erschienen in: Metabolic engineering (2021)
Zelle, E.
Pfelzer, N.
Oldiges, Marco
Koch-Koerfges, A.
Bott, M.
Nöh, K.
Wiechert, W. (Corresponding author)
Microbioreactor‐assisted cultivation workflows for time‐efficient phenotyping of protein producing Aspergillus niger in batch and fed‐batch mode
Erschienen in: Biotechnology progress (2021)
Jansen, Roman
Morschett, Holger
Hasenklever, Dennis
Moch, Matthias
Wiechert, Wolfgang
Oldiges, Marco (Corresponding author)
Need for speed : evaluation of dilute and shoot-mass spectrometry for accelerated metabolic phenotyping in bioprocess development
Erschienen in: Analytical and bioanalytical chemistry (2021)
Reiter, Alexander
Herbst, Laura Marie
Wiechert, Wolfgang
Oldiges, Marco (Corresponding author)
Construction and comprehensive characterization of an EcLDCc-CatIB set—varying linkers and aggregation inducing tags
Erschienen in: Microbial cell factories (2021)
Küsters, Kira
Pohl, Martina
Krauss, Ulrich
Ölçücü, Gizem
Albert, Sandor
Jaeger, Karl-Erich
Wiechert, Wolfgang
Oldiges, Marco (Corresponding author)
pyFOOMB: Python framework for object oriented modeling of bioprocesses
Erschienen in: Engineering in life sciences (2021)
Hemmerich, Johannes
Tenhaef, Niklas
Wiechert, Wolfgang
Noack, Stephan (Corresponding author)
Screening of a genome-reduced Corynebacterium glutamicum strain library for improved heterologous cutinase secretion
Erschienen in: Microbial biotechnology (2020)
Hemmerich, Johannes
Labib, Mohamed
Steffens, Carmen
Reich, Sebastian J.
Weiske, Marc
Baumgart, Meike
Rückert, Christian
Ruwe, Matthias
Siebert, Daniel
Wendisch, Volker F.
Kalinowski, Jörn
Wiechert, Wolfgang
Oldiges, Marco (Corresponding author)
Analysis of the local well‐posedness of optimization‐constrained differential equations by local optimality conditions
Erschienen in: AIChE journal (2020)
Zhao, Xiao
Ploch, Tobias Michael
Noack, Stephan
Wiechert, Wolfgang
Mitsos, Alexander (Corresponding author)
von Lieres und Wilkau, Eric (Corresponding author)
Simulation of differential-algebraic equation systems with optimization criteria embedded in Modelica
Erschienen in: Computers & chemical engineering (2020)
Ploch, Tobias Michael
von Lieres und Wilkau, Eric
Wiechert, Wolfgang
Mitsos, Alexander
Hannemann-Tamás, Ralf (Corresponding author)
Parallelized microscale fed-batch cultivation in online-monitored microtiter plates : implications of media composition and feed strategies for process design and performance
Erschienen in: Journal of industrial microbiology & biotechnology (2019)
Morschett, Holger (Corresponding author)
Jansen, Roman
Neuendorf, Christian
Moch, Matthias
Wiechert, Wolfgang
Oldiges, Marco (Corresponding author)
Comprehensive analysis of metabolic sensitivity of 1,4-butanediol producing Escherichia coli toward substrate and oxygen availability
Erschienen in: Biotechnology progress (2019)
Pooth, Viola
Gaalen, Kathrin
Trenkamp, Sandra
Wiechert, Wolfgang
Oldiges, Marco (Corresponding author)
Combinatorial impact of Sec signal peptides from Bacillus subtilis and bioprocess conditions on heterologous cutinase secretion by Corynebacterium glutamicum
Erschienen in: Biotechnology & bioengineering (2018)
Hemmerich, Johannes
Moch, Matthias
Jurischka, Sarah
Wiechert, Wolfgang
Freudl, Roland
Oldiges, Marco (Corresponding author)
Less Sacrifice, More Insight: Repeated Low-Volume Sampling of Microbioreactor Cultivations Enables Accelerated Deep Phenotyping of Microbial Strain Libraries
Erschienen in: Biotechnology journal (2018)
Hemmerich, Johannes
Tenhaef, Niklas
Steffens, Carmen
Kappelmann, Jannick
Weiske, Marc
Reich, Sebastian J.
Wiechert, Wolfgang
Oldiges, Marco
Noack, Stephan (Corresponding author)
Multiscale dynamic modeling and simulation of a biorefinery
Erschienen in: Biotechnology & bioengineering (2019)
Ploch, Tobias Michael
Zhao, Xiao
Hüser, Jonathan
von Lieres und Wilkau, Eric
Hannemann-Tamás, Ralf
Naumann, Uwe
Wiechert, Wolfgang
Mitsos, Alexander (Corresponding author)
Noack, Stephan (Corresponding author)
Corrigendum: The Design of FluxML: A Universal Modeling Language for 13C Metabolic Flux Analysis
Erschienen in: Frontiers in microbiology (2019)
Beyß, Martin
Azzouzi, Salah
Weitzel, Michael
Wiechert, Wolfgang
Nöh, Katharina (Corresponding author)
The Design of FluxML: A Universal Modeling Language for 13C Metabolic Flux Analysis
Erschienen in: Frontiers in microbiology (2019)
Beyß, Martin
Azzouzi, Salah
Weitzel, Michael
Wiechert, Wolfgang
Nöh, Katharina (Corresponding author)
Quantitative measurements in single-cell analysis: towards scalability in microbial bioprocess development
Erschienen in: Current opinion in biotechnology (2018)
Demling, Philipp
Westerwalbesloh, Christoph
Noack, Stephan
Wiechert, Wolfgang
Kohlheyer, Dietrich
Germination and Growth Analysis of Streptomyces lividans at the Single-Cell Level Under Varying Medium Compositions
Erschienen in: Frontiers in microbiology (2018)
Koepff, Joachim
Sachs, Christian Carsten
Wiechert, Wolfgang
Kohlheyer, Dietrich
Nöh, Katharina
Oldiges, Marco
Grünberger, Alexander (Corresponding author)
Application of Mass Spectrometry-based Metabolomics and Fluxomics for Biotechnological Strain Improvement (2018)Weber, Dieter (Corresponding author)
Beyß, Martin
Mampel, Jörg
Wiechert, Wolfgang
Blank, Lars M.
Nöh, Katharina
Ebert, Birgitta Elisabeth
Framework for Multi-Scale Modeling and Dynamic Simulation of a Biorefinery (2018)Ploch, Tobias Michael
Zhao, Xiao
Tenhaef, Niklas
Hüser, Jonathan
Lieres, von Eric
Hannemann-Tamás, Ralf
Naumann, Uwe
Wiechert, Wolfgang
Mitsos, Alexander (Corresponding author)
Noack, Stephan
HiQFlux: Quantifying metabolic network operation in compartmentalized organisms - yeast as a eukaryotic model (2017)Beyß, Martin
Weber, Dieter
Blank, Lars M.
Wiechert, Wolfgang
Ebert, Birgitta Elisabeth (Corresponding author)
Nöh, Katharina
Homogenizing bacterial cell factories : Analysis and engineering of phenotypic heterogeneity
Erschienen in: Metabolic engineering (2017)
Binder, Dennis (Corresponding author)
Drepper, Thomas
Jaeger, Karl-Erich
Delvigne, Frank
Wiechert, Wolfgang
Kohlheyer, Dietrich
Grünberger, Alexander (Corresponding author)
Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology
Erschienen in: Journal of visualized experiments (2017)
Hemmerich, Johannes
Freier, Lars
Wiechert, Wolfgang
von Lieres und Wilkau, Eric (Corresponding author)
Oldiges, Marco (Corresponding author)
40 Years of Biotechnology Research at Forschungszentrum Jülich
Erschienen in: Journal of biotechnology (2017)
Bott, Michael (Editor)
Jaeger, Karl-Erich (Editor)
Pietruszka, Jörg (Editor)
Wiechert, Wolfgang (Editor)
HiQFlux: Quantifying metabolic network operation in compartmentalized organisms - yeast as a eukaryotic model (2016)Ebert, Birgitta Elisabeth
Nöh, Katharina
Wiechert, Wolfgang
Blank, Lars M.
A Toolbox of Genetically Encoded FRET-Based Biosensors for Rapid l-Lysine Analysis
Erschienen in: Sensors (2016)
Steffen, Victoria
Otten, Julia
Engelmann, Susann
Radek, Andreas
Limberg, Michael
Koenig, Bernd
Noack, Stephan
Wiechert, Wolfgang
Pohl, Martina (Corresponding author)
Photocaged Arabinose: A Novel Optogenetic Switch for Rapid and Gradual Control of Microbial Gene Expression
Erschienen in: ChemBioChem (2016)
Binder, Dennis (Corresponding author)
Bier, Claus
Grünberger, Alexander
Drobietz, Dagmar
Hage-Hülsmann, Jennifer
Wandrey, Georg Benjamin
Büchs, Jochen
Kohlheyer, Dietrich
Loeschcke, Anita
Wiechert, Wolfgang
Jaeger, Karl-Erich
Pietruszka, Jörg
Drepper, Thomas
Rapid assessment of oxygen transfer impact for Corynebacterium glutamicum
Erschienen in: Bioprocess and biosystems engineering (2014)
Käß, Friedrich
Prasad, Arjun
Tillack, Jana
Moch, Matthias
Giese, Heiner
Büchs, Jochen
Wiechert, Wolfgang
Oldiges, Marco (Corresponding author)
First- and Second-Order Parameter Sensitivities of a Metabolically and Isotopically Non-Stationary Biochemical Network Model
Erschienen in: Proceedings - 9th International Modelica Conference : September 3 - 5, 2012, Munich, Germany / , Martin Otter ; Dirk Zimmer (2012)
Hannemann-Tamás, Ralf
Tillack, Jana
Schmitz, Moritz
Förster, Michael
Wyes, Jutta
Nöh, Katharina
von Lieres und Wilkau, Eric
Naumann, Uwe
Wiechert, Wolfgang
Marquardt, Wolfgang