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Publications

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Publications

Titel	Author(s)
Microaerobic growth‐decoupled production of α‐ketoglutarate and succinate from xylose in a one‐pot process using Corynebacterium glutamicum Erschienen in: Biotechnology journal (2021)	Tenhaef, Niklas Kappelmann, Jannick Eich, Arabel Weiske, Marc Brieß, Lisette Brüsseler, Christian Marienhagen, Jan Wiechert, Wolfgang Noack, Stephan (Corresponding author)
Robotic integration enables autonomous operation of laboratory scale stirred tank bioreactors with model-driven process analysis Erschienen in: Biotechnology & bioengineering (2021)	Morschett, Holger Tenhaef, Niklas Hemmerich, Johannes Herbst, Laura Spiertz, Markus Dogan, Deniz Wiechert, Wolfgang Noack, Stephan Oldiges, Marco (Corresponding author)
Microbioreactor‐assisted cultivation workflows for time‐efficient phenotyping of protein producing Aspergillus niger in batch and fed‐batch mode Erschienen in: Biotechnology progress (2021)	Jansen, Roman Morschett, Holger Hasenklever, Dennis Moch, Matthias Wiechert, Wolfgang Oldiges, Marco (Corresponding author)
Need for speed : evaluation of dilute and shoot-mass spectrometry for accelerated metabolic phenotyping in bioprocess development Erschienen in: Analytical and bioanalytical chemistry (2021)	Reiter, Alexander Herbst, Laura Marie Wiechert, Wolfgang Oldiges, Marco (Corresponding author)
Construction and comprehensive characterization of an EcLDCc-CatIB set—varying linkers and aggregation inducing tags Erschienen in: Microbial cell factories (2021)	Küsters, Kira Pohl, Martina Krauss, Ulrich Ölçücü, Gizem Albert, Sandor Jaeger, Karl-Erich Wiechert, Wolfgang Oldiges, Marco (Corresponding author)
pyFOOMB: Python framework for object oriented modeling of bioprocesses Erschienen in: Engineering in life sciences (2021)	Hemmerich, Johannes Tenhaef, Niklas Wiechert, Wolfgang Noack, Stephan (Corresponding author)
Screening of a genome‐reduced Corynebacterium glutamicum strain library for improved heterologous cutinase secretion Erschienen in: Microbial biotechnology (2020)	Hemmerich, Johannes Labib, Mohamed Steffens, Carmen Reich, Sebastian J. Weiske, Marc Baumgart, Meike Rückert, Christian Ruwe, Matthias Siebert, Daniel Wendisch, Volker F. Kalinowski, Jörn Wiechert, Wolfgang Oldiges, Marco (Corresponding author)
Analysis of the local well‐posedness of optimization‐constrained differential equations by local optimality conditions Erschienen in: AIChE journal (2020)	Zhao, Xiao Ploch, Tobias Michael Noack, Stephan Wiechert, Wolfgang Mitsos, Alexander (Corresponding author) von Lieres, Eric (Corresponding author)
Simulation of differential-algebraic equation systems with optimization criteria embedded in Modelica Erschienen in: Computers & chemical engineering (2020)	Ploch, Tobias Michael von Lieres, Eric Wiechert, Wolfgang Mitsos, Alexander Hannemann-Tamás, Ralf (Corresponding author)
Parallelized microscale fed-batch cultivation in online-monitored microtiter plates : implications of media composition and feed strategies for process design and performance Erschienen in: Journal of industrial microbiology & biotechnology (2019)	Morschett, Holger (Corresponding author) Jansen, Roman Neuendorf, Christian Moch, Matthias Wiechert, Wolfgang Oldiges, Marco (Corresponding author)
Comprehensive analysis of metabolic sensitivity of 1,4-butanediol producing Escherichia coli toward substrate and oxygen availability Erschienen in: Biotechnology progress (2019)	Pooth, Viola Gaalen, Kathrin Trenkamp, Sandra Wiechert, Wolfgang Oldiges, Marco (Corresponding author)
Combinatorial impact of Sec signal peptides from Bacillus subtilis and bioprocess conditions on heterologous cutinase secretion by Corynebacterium glutamicum Erschienen in: Biotechnology & bioengineering (2018)	Hemmerich, Johannes Moch, Matthias Jurischka, Sarah Wiechert, Wolfgang Freudl, Roland Oldiges, Marco (Corresponding author)
Less Sacrifice, More Insight: Repeated Low-Volume Sampling of Microbioreactor Cultivations Enables Accelerated Deep Phenotyping of Microbial Strain Libraries Erschienen in: Biotechnology journal (2018)	Hemmerich, Johannes Tenhaef, Niklas Steffens, Carmen Kappelmann, Jannick Weiske, Marc Reich, Sebastian J. Wiechert, Wolfgang Oldiges, Marco Noack, Stephan (Corresponding author)
Multiscale dynamic modeling and simulation of a biorefinery Erschienen in: Biotechnology & bioengineering (2019)	Ploch, Tobias Michael Zhao, Xiao Hüser, Jonathan von Lieres, Eric Hannemann-Tamás, Ralf Naumann, Uwe Wiechert, Wolfgang Mitsos, Alexander (Corresponding author) Noack, Stephan (Corresponding author)
Corrigendum: The Design of FluxML: A Universal Modeling Language for 13C Metabolic Flux Analysis Erschienen in: Frontiers in microbiology (2019)	Beyß, Martin Azzouzi, Salah Weitzel, Michael Wiechert, Wolfgang Nöh, Katharina (Corresponding author)
The Design of FluxML: A Universal Modeling Language for 13C Metabolic Flux Analysis Erschienen in: Frontiers in microbiology (2019)	Beyß, Martin Azzouzi, Salah Weitzel, Michael Wiechert, Wolfgang Nöh, Katharina (Corresponding author)
Quantitative measurements in single-cell analysis: towards scalability in microbial bioprocess development Erschienen in: Current opinion in biotechnology (2018)	Demling, Philipp Westerwalbesloh, Christoph Noack, Stephan Wiechert, Wolfgang Kohlheyer, Dietrich
Germination and Growth Analysis of Streptomyces lividans at the Single-Cell Level Under Varying Medium Compositions Erschienen in: Frontiers in microbiology (2018)	Koepff, Joachim Sachs, Christian Carsten Wiechert, Wolfgang Kohlheyer, Dietrich Nöh, Katharina Oldiges, Marco Grünberger, Alexander (Corresponding author)
Application of Mass Spectrometry-based Metabolomics and Fluxomics for Biotechnological Strain Improvement (2018)	Weber, Dieter (Corresponding author) Beyß, Martin Mampel, Jörg Wiechert, Wolfgang Blank, Lars M. Nöh, Katharina Ebert, Birgitta Elisabeth
Framework for Multi-Scale Modeling and Dynamic Simulation of a Biorefinery (2018)	Ploch, Tobias Zhao, Xiao Tenhaef, Niklas Hüser, Jonathan Lieres, von Eric Hannemann-Tamás, Ralf Naumann, Uwe Wiechert, Wolfgang Mitsos, Alexander (Corresponding author) Noack, Stephan
HiQFlux: Quantifying metabolic network operation in compartmentalized organisms - yeast as a eukaryotic model (2017)	Beyß, Martin Weber, Dieter Blank, Lars M. Wiechert, Wolfgang Ebert, Birgitta Elisabeth (Corresponding author) Nöh, Katharina
Homogenizing bacterial cell factories : Analysis and engineering of phenotypic heterogeneity Erschienen in: Metabolic engineering (2017)	Binder, Dennis (Corresponding author) Drepper, Thomas Jaeger, Karl-Erich Delvigne, Frank Wiechert, Wolfgang Kohlheyer, Dietrich Grünberger, Alexander (Corresponding author)
Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology Erschienen in: Journal of visualized experiments (2017)	Hemmerich, Johannes Freier, Lars Wiechert, Wolfgang von Lieres, Eric (Corresponding author) Oldiges, Marco (Corresponding author)
40 Years of Biotechnology Research at Forschungszentrum Jülich Erschienen in: Journal of biotechnology (2017)	Bott, Michael (Editor) Jaeger, Karl-Erich (Editor) Pietruszka, Jörg (Editor) Wiechert, Wolfgang (Editor)
HiQFlux: Quantifying metabolic network operation in compartmentalized organisms - yeast as a eukaryotic model (2016)	Ebert, Birgitta Elisabeth Nöh, Katharina Wiechert, Wolfgang Blank, Lars M.
A Toolbox of Genetically Encoded FRET-Based Biosensors for Rapid l-Lysine Analysis Erschienen in: Sensors (2016)	Steffen, Victoria Otten, Julia Engelmann, Susann Radek, Andreas Limberg, Michael Koenig, Bernd Noack, Stephan Wiechert, Wolfgang Pohl, Martina (Corresponding author)
Photocaged Arabinose: A Novel Optogenetic Switch for Rapid and Gradual Control of Microbial Gene Expression Erschienen in: ChemBioChem (2016)	Binder, Dennis (Corresponding author) Bier, Claus Grünberger, Alexander Drobietz, Dagmar Hage-Hülsmann, Jennifer Wandrey, Georg Benjamin Büchs, Jochen Kohlheyer, Dietrich Loeschcke, Anita Wiechert, Wolfgang Jaeger, Karl-Erich Pietruszka, Jörg Drepper, Thomas
Rapid assessment of oxygen transfer impact for Corynebacterium glutamicum Erschienen in: Bioprocess and biosystems engineering (2014)	Käß, Friedrich Prasad, Arjun Tillack, Jana Moch, Matthias Giese, Heiner Büchs, Jochen Wiechert, Wolfgang Oldiges, Marco (Corresponding author)
First- and Second-Order Parameter Sensitivities of a Metabolically and Isotopically Non-Stationary Biochemical Network Model Erschienen in: Proceedings - 9th International Modelica Conference : September 3 - 5, 2012, Munich, Germany / , Martin Otter ; Dirk Zimmer (2012)	Hannemann-Tamás, Ralf Tillack, Jana Schmitz, Moritz Förster, Michael Wyes, Jutta Nöh, Katharina von Lieres, Eric Naumann, Uwe Wiechert, Wolfgang Marquardt, Wolfgang